Neuroblastoma is a cancer that forms in your nerve tissue. It usually begins in the adrenal glands, which sit atop your kidneys. It may also begin in your neck, chest or spinal cord. The cancer often begins in early childhood. Sometimes it begins before a child is born. By the time doctors find the cancer, it has usually spread to other parts of the body. The most common symptoms are
- A lump in the abdomen, neck or chest
- Bulging eyes
- Dark circles around the eyes
- Bone pain
- Swollen stomach and trouble breathing in babies
- Painless, bluish lumps under the skin in babies
- Inability to move a body part
Treatments include surgery, radiation therapy, chemotherapy, biologic therapy, or a combination. Biologic therapy boosts your body's own ability to fight cancer. Sometimes before giving treatment, doctors wait to see whether symptoms get worse. This is called watchful waiting.
NIH: National Cancer Institute
Diagnosis and Tests
- How Is Neuroblastoma Diagnosed? (American Cancer Society)
- Neuroblastoma in Children: Just Diagnosed Information (CureSearch for Children's Cancer)
- Neuroblastoma Screening (National Cancer Institute) Also in Spanish
- VMA Test (American Association for Clinical Chemistry)
Treatments and Therapies
- Neuroblastoma Treatment (National Cancer Institute)
- Do We Know What Causes Neuroblastoma? (American Cancer Society)
- Genetics Home Reference: neuroblastoma (National Library of Medicine)
Statistics and Research
- What Are the Key Statistics about Neuroblastoma? (American Cancer Society)
- What's New in Neuroblastoma Research and Treatment? (American Cancer Society)
- ClinicalTrials.gov: Neuroblastoma (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Orbital neuroblastoma metastasis: A case report and literature review.
- Article: Management of tumor rupture and abdominal compartment syndrome in an infant...
- Article: Pediatric minimally invasive surgery for malignant abdominal tumor: Single center experience.
- Neuroblastoma -- see more articles