Diabetes insipidus (DI) causes frequent urination. You become extremely thirsty, so you drink. Then you urinate. This cycle can keep you from sleeping or even make you wet the bed. Your body produces lots of urine that is almost all water.
DI is different from diabetes mellitus (DM), which involves insulin problems and high blood sugar. The symptoms can be similar. However, DI is related to how your kidneys handle fluids. It's much less common than DM. Urine and blood tests can show which one you have.
Usually, DI is caused by a problem with your pituitary gland or your kidneys. Treatment depends on the cause of the problem. Medicines can often help.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
- Nephrogenic diabetes insipidus: MedlinePlus Genetics (National Library of Medicine)
- Neurohypophyseal diabetes insipidus: MedlinePlus Genetics (National Library of Medicine)
- Wolfram syndrome: MedlinePlus Genetics (National Library of Medicine)
- ClinicalTrials.gov: Diabetes Insipidus (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Urine concentration impairment in sickle cell anemia: genuine nephrogenic diabetes insipidus...
- Article: Nuclear translocation of beta catenin in patients with Rathke cleft cysts-clinical...
- Article: Characteristics and factors influencing hypothalamic pituitary dysfunction in patients with craniopharyngioma.
- Diabetes Insipidus -- see more articles