Clostridium difficile (C. difficile) is a bacterium that causes diarrhea and more serious intestinal conditions such as colitis. Symptoms include
- Watery diarrhea (at least three bowel movements per day for two or more days)
- Loss of appetite
- Abdominal pain or tenderness
You might get C. difficile disease if you have an illness that requires prolonged use of antibiotics. Increasingly, the disease can also be spread in the hospital. The elderly are also at risk. Treatment is with antibiotics.
Centers for Disease Control and Prevention
- Study Suggests Heartburn Meds-Superbug Infections Link (03/27/2017, HealthDay)
Diagnosis and Tests
- Clostridium difficile and C. difficile Toxin Testing (American Association for Clinical Chemistry)
- Antibiotic-Associated Diarrhea (Mayo Foundation for Medical Education and Research)
- Information about the Current Strain of Clostridium difficile (Centers for Disease Control and Prevention)
- Pseudomembranous colitis (Mayo Foundation for Medical Education and Research)
- ClinicalTrials.gov: Clostridium difficile Infections (National Institutes of Health)
- ClinicalTrials.gov: Enterocolitis, Pseudomembranous (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Recurrent Clostridium difficile infection among Medicare patients in nursing homes:...
- Article: Clostridium difficile infection in inflammatory bowel disease: challenges in diagnosis...
- Article: Subtyping and antimicrobial susceptibility of Clostridium difficile PCR ribotype 078/126...
- Clostridium Difficile Infections -- see more articles
- Special Concerns for Seniors: Clostridium difficile (Alliance for the Prudent Use of Antibiotics)