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Summary
The anus is where stool leaves your body when you go to the bathroom. It is made up of your outer layers of skin and the end of your large intestine. Anal cancer is a disease in which cancer cells form in the tissues of the anus.
Anal cancer is rare. It is more common in smokers and people over 50. You are also at higher risk if you have HPV, have anal sex, or have many sexual partners.
Symptoms include bleeding, pain, or lumps in the anal area. Anal itching and discharge can also be signs of anal cancer.
Doctors use tests that examine the anus to diagnose anal cancer. They include a physical exam, endoscopy, ultrasound, and biopsy.
Treatments include radiation therapy, chemotherapy, and surgery.
NIH: National Cancer Institute
Diagnosis and Tests
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Anoscopy
(National Library of Medicine) Also in Spanish
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Stages of Anal Cancer
(National Cancer Institute) Also in Spanish
- Tests for Anal Cancer (American Cancer Society)
Prevention and Risk Factors
- Digital Rectal Exam (DRE) (American Society of Clinical Oncology) Also in Spanish
- Risk Factors for Anal Cancer (American Cancer Society)
Treatments and Therapies
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Drugs Approved for Anal Cancer
(National Cancer Institute)
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External Beam Radiation Therapy for Cancer
(National Cancer Institute) Also in Spanish
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Treatment Option Overview (Anal Cancer)
(National Cancer Institute) Also in Spanish
Living With
- Living as an Anal Cancer Survivor (American Cancer Society)
Related Issues
- Anal Warts (American Society of Colon and Rectal Surgeons) Also in Spanish
- What Causes Anal Cancer? (American Cancer Society)
Statistics and Research
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Cancer of the Anus
(National Cancer Institute)
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Electrocautery Superior to Topical Treatments for Precancerous Anal Lesions
(National Cancer Institute)
Clinical Trials
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ClinicalTrials.gov: Anus Neoplasms
(National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Evaluation of the validity of the HPV viral load compared to...
- Article: Exploring Patients' Perspectives on Late Complications after Colorectal and Anal Cancer...
- Article: Effectiveness and cost-effectiveness of human papillomavirus vaccination strategies among men who...
- Anal Cancer -- see more articles
Reference Desk
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Dictionary of Cancer Terms
(National Cancer Institute) Also in Spanish
Find an Expert
- American Cancer Society
- Find a Cancer Doctor (American Society of Clinical Oncology)
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National Cancer Institute
Also in Spanish
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National Institute of Diabetes and Digestive and Kidney Diseases
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Organizations that Offer Cancer Support Services
(National Cancer Institute) Also in Spanish
Patient Handouts
- After chemotherapy - discharge (Medical Encyclopedia) Also in Spanish
- Anal cancer (Medical Encyclopedia) Also in Spanish
- Anoscopy (Medical Encyclopedia) Also in Spanish
- Pelvic radiation - discharge (Medical Encyclopedia) Also in Spanish