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Summary
Skin cancer is the most common form of cancer in the United States. The two most common types are basal cell cancer and squamous cell cancer. They usually form on the head, face, neck, hands, and arms. Another type of skin cancer, melanoma, is more dangerous but less common.
Anyone can get skin cancer, but it is more common in people who :
- Spend a lot of time in the sun or have been sunburned
- Have light-colored skin, hair and eyes
- Have a family member with skin cancer
- Are over age 50
You should have your doctor check any suspicious skin markings and any changes in the way your skin looks. Treatment is more likely to work well when cancer is found early. If not treated, some types of skin cancer cells can spread to other tissues and organs. Treatments include surgery, radiation therapy, chemotherapy, photodynamic therapy (PDT), and biologic therapy. PDT uses a drug and a type of laser light to kill cancer cells. Biologic therapy boosts your body's own ability to fight cancer.
NIH: National Cancer Institute
Diagnosis and Tests
- How Are Squamous and Basal Cell Skin Cancers Diagnosed? (American Cancer Society) Also in Spanish
- Skin Biopsy (VisualDX)
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Skin Cancer Screening
(National Library of Medicine) Also in Spanish
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Skin Cancer Screening
(National Cancer Institute) Also in Spanish
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Stages of Merkel Cell Carcinoma
(National Cancer Institute) Also in Spanish
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Stages of Skin Cancer
(National Cancer Institute) Also in Spanish
Prevention and Risk Factors
- Behavioral Counseling to Prevent Skin Cancer (U.S. Preventive Services Task Force) - PDF
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Skin Cancer Prevention
(National Cancer Institute) Also in Spanish
- Surgeon General's Call to Action to Prevent Skin Cancer (Centers for Disease Control and Prevention; Surgeon General)
Treatments and Therapies
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Cryosurgery to Treat Cancer
(National Cancer Institute) Also in Spanish
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Drugs Approved for Skin Cancer
(National Cancer Institute)
- Electrodesiccation (VisualDX)
- Mohs Micrographic Surgery (VisualDX)
- Skin Cancer: Treatment Types (American Society for Radiation Oncology)
-
Treatment of Actinic Keratosis
(National Cancer Institute) Also in Spanish
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Treatment Option Overview (Merkel Cell Carcinoma)
(National Cancer Institute) Also in Spanish
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Treatment Option Overview (Skin Cancer)
(National Cancer Institute)
Living With
- What Will Happen After Treatment for Basal and Squamous Cell Skin Cancers? (American Cancer Society) Also in Spanish
Related Issues
- Actinic Cheilitis (VisualDX)
- Actinic Keratosis (Solar Keratosis) (VisualDX)
-
Anyone Can Get Skin Cancer
(National Cancer Institute) - PDF Also in Spanish
-
Risks of Skin Cancer Screening
(National Cancer Institute) Also in Spanish
- Sunscreen: How to Help Protect Your Skin from the Sun (Food and Drug Administration)
Specifics
- Eyelid Cancer (American Society of Clinical Oncology)
-
General Information about Merkel Cell Carcinoma
(National Cancer Institute) Also in Spanish
- Nevoid Basal Cell Carcinoma Syndrome (American Society of Clinical Oncology)
- Sebaceous Carcinoma: Overview (American Academy of Dermatology)
- Skin Cancer of the Hand and Upper Extremity (American Society for Surgery of the Hand)
Genetics
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9q22.3 microdeletion: MedlinePlus Genetics
(National Library of Medicine)
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Gorlin syndrome: MedlinePlus Genetics
(National Library of Medicine)
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Learning about Skin Cancer
(National Human Genome Research Institute)
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Xeroderma pigmentosum: MedlinePlus Genetics
(National Library of Medicine)
Images
- Squamous Cell Carcinoma (SCC) (VisualDX)
Statistics and Research
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Advances in Melanoma and Other Skin Cancers Research
(National Cancer Institute)
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For Some Skin Cancers, Targeted Drug Hits the Mark
(National Cancer Institute)
- Melanoma of the Skin Statistics (Centers for Disease Control and Prevention)
- Skin Cancer (American Academy of Dermatology)
- What's New in Research and Treatment of Basal and Squamous Cell Skin Cancers? (American Cancer Society) Also in Spanish
Clinical Trials
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ClinicalTrials.gov: Carcinoma, Basal Cell
(National Institutes of Health)
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ClinicalTrials.gov: Carcinoma, Merkel Cell
(National Institutes of Health)
-
ClinicalTrials.gov: Keratosis, Actinic
(National Institutes of Health)
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ClinicalTrials.gov: Skin Neoplasms
(National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Single or Daily Application of Topical Curcumin Prevents Ultraviolet B-Induced Apoptosis...
- Article: Efficacy and safety of lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL)...
- Article: Prognostic model for predicting overall and cancer-specific survival among patients with...
- Skin Cancer -- see more articles
Reference Desk
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Dictionary of Cancer Terms
(National Cancer Institute) Also in Spanish
Find an Expert
- American Academy of Dermatology
- American Cancer Society
- Find a Cancer Doctor (American Society of Clinical Oncology)
- Find a Dermatologic Surgeon (American Society for Dermatologic Surgery)
- Find a Dermatologist (American Academy of Dermatology)
-
National Cancer Institute
Also in Spanish
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Organizations that Offer Cancer Support Services
(National Cancer Institute) Also in Spanish
Children
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Childhood Basal Cell Carcinoma and Squamous Cell Carcinoma of the Skin Treatment
(National Cancer Institute) Also in Spanish
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Childhood Melanoma Treatment
(National Cancer Institute) Also in Spanish
Patient Handouts
- Basal cell carcinoma (Medical Encyclopedia) Also in Spanish
- Mohs micrographic surgery (Medical Encyclopedia) Also in Spanish
- Skin lesion biopsy (Medical Encyclopedia) Also in Spanish
- Skin self-exam (Medical Encyclopedia) Also in Spanish
- Squamous cell skin cancer (Medical Encyclopedia) Also in Spanish