What is delirium?
Delirium is a mental state in which you are confused, disoriented, and not able to think or remember clearly. It usually starts suddenly. It is often temporary and treatable.
There are three types of delirium:
- Hypoactive, where you are not active and seem sleepy, tired, or depressed
- Hyperactive, where you are restless or agitated
- Mixed, where you change back and forth between being hypoactive and hyperactive
What causes delirium?
There are many different problems that can cause delirium. Some of the more common causes include
- Alcohol or drugs, either from intoxication or withdrawal. This includes a serious type of alcohol withdrawal syndrome called delirium tremens. It usually happens to people who stop drinking after years of alcohol abuse.
- Dehydration and electrolyte imbalances
- Hospitalization, especially in intensive care
- Infections, such as urinary tract infections, pneumonia, and the flu
- Medicines. This could be a side effect of a medicine, such as sedatives or opioids. Or it could be withdrawal after stopping a medicine.
- Metabolic disorders
- Organ failure, such as kidney or liver failure
- Serious illnesses
- Severe pain
- Sleep deprivation
- Surgeries, including reactions to anesthesia
Who is at risk for delirium?
Certain factors put you at risk for delirium, including
- Being in a hospital or nursing home
- Having a serious illness or more than one illness
- Having an infection
- Older age
- Taking medicines that affect the mind or behavior
- Taking high doses of pain medicines, such as opioids
What are the symptoms of delirium?
The symptoms of delirium usually start suddenly, over a few hours or a few days. They often come and go. The most common symptoms include
- Changes in alertness (usually more alert in the morning, less at night)
- Changing levels of consciousness
- Disorganized thinking, talking in a way that doesn't make sense
- Disrupted sleep patterns, sleepiness
- Emotional changes: anger, agitation, depression, irritability, overexcitement
- Hallucinations and delusions
- Memory problems, especially with short-term memory
- Trouble concentrating
How is delirium diagnosed?
Your health care provider may use many tools to make a diagnosis:
- A medical history, which includes asking about your symptoms
- Physical and neurological exams
- Mental status testing
- Lab and diagnostic imaging tests
Delirium and dementia have similar symptoms, so it can be hard to tell them apart. They can also occur together. Delirium starts suddenly and can cause hallucinations. The symptoms may get better or worse and can last for hours or weeks. On the other hand, dementia develops slowly and does not cause hallucinations. The symptoms are stable and may last for months or years.
What are the treatments for delirium?
Treatment of delirium focuses on the causes and symptoms of delirium. The first step is to identify the cause. Often, treating the cause will lead to a full recovery. The recovery may take some time - weeks or sometimes even months. In the meantime, there may be treatments to manage the symptoms, such as
- Controlling the environment, which includes making sure that the room is quiet and well-lit, having clocks or calendars in view, and having family members around
- Medicines, including those that control aggression or agitation and pain relievers if there is pain
- If needed, making sure that the person has a hearing aid, glasses, or other devices for communication
Can delirium be prevented?
Treating the conditions that can cause delirium may reduce the risk of getting it. Hospitals can help lower the risk of delirium by avoiding sedatives and making sure that the room is kept quiet, calm, and well-lit. It can also help to have family members around and to have the same staff members treat the person.
- Delirium (Merck & Co., Inc.) Also in Spanish
- Delirium (PDQ) (National Cancer Institute) Also in Spanish
- Delirium: Issues for Older Adults (AGS Foundation for Health in Aging)
- National Institute of Neurological Disorders and Stroke Also in Spanish
- The Dilemma of Delirium in Older Patients (National Institute on Aging)
- What to Ask: Delirium (AGS Foundation for Health in Aging)
- ClinicalTrials.gov: Delirium (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Effect of remimazolam besylate compared with propofol on the incidence of...
- Article: Relationship among melatonin, postoperative delirium, and postoperative cognitive dysfunction.
- Article: Risk of delirium and impaired neurological outcome associated with delay in...
- Delirium -- see more articles