Autonomic Nervous System Disorders

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Basics

• Summary
• Start Here
• Diagnosis and Tests
• Learn More

Learn More

• Specifics
• Genetics

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Research

• Clinical Trials
• Journal Articles

Resources

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For You

• Children
• Patient Handouts

Summary

Your autonomic nervous system is the part of your nervous system that controls involuntary actions, such as the beating of your heart and the widening or narrowing of your blood vessels. When something goes wrong in this system, it can cause serious problems, including:

• Blood pressure problems
• Heart problems
• Trouble with breathing and swallowing
• Erectile dysfunction in men

Autonomic nervous system disorders can occur alone or as the result of another disease, such as Parkinson's disease, alcoholism and diabetes. Problems can affect either part of the system, as in complex regional pain syndromes, or all of the system. Some types are temporary, but many worsen over time. When they affect your breathing or heart function, these disorders can be life-threatening.

Some autonomic nervous system disorders get better when an underlying disease is treated. Often, however, there is no cure. In that case, the goal of treatment is to improve symptoms.

NIH: National Institute of Neurological Disorders and Stroke

Start Here

• Autonomic Neuropathy (Mayo Foundation for Medical Education and Research) Also in Spanish
• Overview of the Autonomic Nervous System (Merck & Co., Inc.) Also in Spanish

Diagnosis and Tests

• Autonomic Testing (National Library of Medicine) Also in Spanish

Learn More

• Recognizing POTS: Learn to Spot This Mysterious Condition (National Institutes of Health) Also in Spanish

Specifics

• Congenital Central Hypoventilation Syndrome (Genetic and Rare Diseases Information Center)
• Holmes-Adie Syndrome (National Institute of Neurological Disorders and Stroke)
• Horner Syndrome (Mayo Foundation for Medical Education and Research)
• Multiple System Atrophy (National Institute of Neurological Disorders and Stroke) Also in Spanish
• Orthostatic Hypotension (Postural Hypotension) (Mayo Foundation for Medical Education and Research) Also in Spanish
• Postural Tachycardia Syndrome (POTS) (National Institute of Neurological Disorders and Stroke)
• Pure Autonomic Failure (Genetic and Rare Diseases Information Center)

Genetics

• Autosomal dominant leukodystrophy with autonomic disease: MedlinePlus Genetics (National Library of Medicine)
• Cold-induced sweating syndrome: MedlinePlus Genetics (National Library of Medicine)
• Congenital central hypoventilation syndrome: MedlinePlus Genetics (National Library of Medicine)
• Dopamine beta-hydroxylase deficiency: MedlinePlus Genetics (National Library of Medicine)
• Familial dysautonomia: MedlinePlus Genetics (National Library of Medicine)
• Horner syndrome: MedlinePlus Genetics (National Library of Medicine)
• Multiple system atrophy: MedlinePlus Genetics (National Library of Medicine)
• Orthostatic hypotension: MedlinePlus Genetics (National Library of Medicine)
• Stüve-Wiedemann syndrome: MedlinePlus Genetics (National Library of Medicine)
• Transthyretin amyloidosis: MedlinePlus Genetics (National Library of Medicine)
• Triple A syndrome: MedlinePlus Genetics (National Library of Medicine)
• Tyrosine hydroxylase deficiency: MedlinePlus Genetics (National Library of Medicine)

Clinical Trials

• ClinicalTrials.gov: Autonomic Nervous System Diseases (National Institutes of Health)
• ClinicalTrials.gov: Hypotension, Orthostatic (National Institutes of Health)
• ClinicalTrials.gov: Multiple System Atrophy (National Institutes of Health)
• ClinicalTrials.gov: Postural Orthostatic Tachycardia Syndrome (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

• Article: Cardiovascular autonomic neuropathy and the risk of diabetic kidney disease.
• Article: Influence of autonomic nervous dysfunction on eating during hemodialysis sessions: An...
• Article: Persistent Autonomic and Immunologic Abnormalities in Neurologic Post-Acute Sequelae of SARS-CoV2...
• Autonomic Nervous System Disorders -- see more articles

Find an Expert

• National Institute of Neurological Disorders and Stroke Also in Spanish

Children

• Anisocoria and Horner's Syndrome (American Association for Pediatric Ophthalmology and Strabismus)
• Postural Orthostatic Tachycardia Syndrome (POTS) (For Parents) (Nemours Foundation) Also in Spanish

Patient Handouts

• Autonomic neuropathy (Medical Encyclopedia) Also in Spanish
• Multiple system atrophy - parkinsonian type (Medical Encyclopedia) Also in Spanish