What is aplastic anemia?
Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make enough new blood cells. It happens when there is damage to stem cells inside your bone marrow. There are different types of aplastic anemia, including Fanconi anemia.
What causes aplastic anemia?
The causes of aplastic anemia can include:
- Autoimmune disorders, which are the most common cause
- Certain inherited gene changes, such as the one that can cause Fanconi anemia
- Toxic substances, such as pesticides, arsenic, and benzene
- Radiation therapy and chemotherapy for cancer
- Certain medicines
- Viral infections such as hepatitis, Epstein-Barr virus, or HIV
In many people, the cause is unknown. This is called idiopathic aplastic anemia.
What are the symptoms of aplastic anemia?
Aplastic anemia can develop suddenly or slowly. It can be mild or severe. The symptoms of aplastic anemia can include:
What other problems can aplastic anemia cause?
Aplastic anemia can cause other problems, including frequent infections and bleeding. It raises your risk of developing a serious blood disorder.
How is aplastic anemia diagnosed?
To find out if you have aplastic anemia, your doctor will:
- Take your medical and your family medical histories
- Do a physical exam
- Order tests, such as tests to check if you have low numbers of cells in your bone marrow and blood
What are the treatments for aplastic anemia?
If you have aplastic anemia, your doctor will create a treatment plan for you. The plan will be based on how severe the anemia is and what is causing it. Treatments can include:
Because of the risk of blood disorders, your doctor will monitor your condition and screen you for blood disorders regularly.
NIH: National Heart, Lung, and Blood Institute
- Aplastic Anemia (National Heart, Lung, and Blood Institute)
- Special Issues for People with Aplastic Anemia (Aplastic Anemia & MDS International Foundation)
- Fanconi anemia: MedlinePlus Genetics (National Library of Medicine)
- ClinicalTrials.gov: Anemia, Aplastic (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Long-term follow-up of haploidentical transplantation in relapsed/refractory severe aplastic anemia: a...
- Article: Anti-Thymocyte Globulin (ATG)-Free Nonmyeloablative Haploidentical PBSCT Plus Post-Transplantation Cyclophosphamide Is a...
- Article: Dyskeratosis congenita and telomere biology disorders.
- Aplastic Anemia -- see more articles