- Toxic substances, such as pesticides, arsenic, and benzene
- Radiation therapy and chemotherapy for cancer
- Certain medicines
- Infections such as hepatitis, Epstein-Barr virus, or HIV
- Autoimmune disorders
- Certain inherited conditions
In many people, the cause is unknown.
Symptoms include fatigue, weakness, dizziness, and shortness of breath. It can cause heart problems such as an irregular heartbeat, an enlarged heart, and heart failure. You may also have frequent infections and bleeding.
Your doctor will diagnose aplastic anemia based on your medical and family histories, a physical exam, and test results. Once your doctor knows the cause and severity of the condition, he or she can create a treatment plan for you. Treatments include blood transfusions, blood and marrow stem cell transplants, and medicines.
NIH: National Heart, Lung, and Blood Institute
- Aplastic Anemia (National Heart, Lung, and Blood Institute)
- Special Issues for People with Aplastic Anemia (Aplastic Anemia & MDS International Foundation)
- Genetics Home Reference: Fanconi anemia (National Library of Medicine)
- ClinicalTrials.gov: Anemia, Aplastic (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia...
- Article: Wilms' tumor 1 mRNA expression: a good tool for differentiating between...
- Article: Abnormal expression of b10 cell frequencies: possible relation to pathogenesis and...
- Aplastic Anemia -- see more articles