Hemophilia is a rare disorder in which the blood does not clot normally. It is usually inherited. Hemophilia usually occurs in males.
If you have hemophilia, you have little or no clotting factor. Clotting factor is a protein needed for normal blood clotting. Without it, you may bleed for a long time after an injury or accident. You also may bleed into your knees, ankles, and elbows. Bleeding in the joints causes pain and, if not treated, can lead to arthritis. Bleeding in the brain, a very serious complication of hemophilia, requires emergency treatment.
The main symptoms of hemophilia are excessive bleeding and easy bruising. Blood tests can tell if you have it. The main treatment is injecting the missing clotting factor into the bloodstream. You may need it on a regular basis, or just when bleeding occurs.
NIH: National Heart, Lung, and Blood Institute
- Frequently Asked Questions: Hemophilia (World Federation of Hemophilia)
- Hemophilia Facts (Centers for Disease Control and Prevention)
- Hemophilia in Pictures (World Federation of Hemophilia) Also in Spanish
- Learning about Hemophilia (National Human Genome Research Institute)
- What is Hemophilia? (National Heart, Lung, and Blood Institute) Also in Spanish
Diagnosis and Tests
- Coagulation Factor Tests (National Library of Medicine) Also in Spanish
- Fibrinogen Test (American Association for Clinical Chemistry)
- Hemophilia Diagnosis (Centers for Disease Control and Prevention) Also in Spanish
- Partial Thromboplastin Time (PTT) Test (National Library of Medicine) Also in Spanish
- PT and INR Test (American Association for Clinical Chemistry)
- Genetics Home Reference: hemophilia (National Library of Medicine)
Statistics and Research
- Hemophilia Data and Statistics (Centers for Disease Control and Prevention)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Factor VIII: Long-established role in haemophilia A and emerging evidence beyond...
- Article: Inflammatory and immune response genes: A genetic analysis of inhibitor development...
- Article: Impact of Prophylaxis on Bone Mineral Metabolism in Children With Hemophilia.
- Hemophilia -- see more articles
- Hemophilia (For Parents) (Nemours Foundation)
- Familiy Planning and Pregnancy (World Federation of Hemophilia)