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These arteries can become blocked with atherosclerotic plaque. Symptoms of such a blockage include pain, most frequently in the foot and calf, and ulcers and non-healing sores of the foot and leg.
Review Date 4/28/2026
Updated by: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.