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Summary
Your liver makes a digestive juice called bile. Your gallbladder stores it between meals. When you eat, your gallbladder pushes the bile into tubes called bile ducts. They carry the bile to your small intestine. The bile helps break down fat. It also helps the liver get rid of toxins and wastes.
Bile duct cancer is rare. It can happen in the parts of the bile ducts that are outside or inside the liver. Cancer of the bile duct outside of the liver is much more common. Risk factors include having inflammation of the bile duct, ulcerative colitis, and some liver diseases.
Symptoms can include:
- Jaundice
- Itchy skin
- Fever
- Abdominal pain
Tests to diagnose bile duct cancer may include a physical exam, imaging tests of the liver and bile ducts, blood tests, and a biopsy.
Treatments include surgery, radiation therapy, and chemotherapy.
NIH: National Cancer Institute
Diagnosis and Tests
- Alkaline Phosphatase (National Library of Medicine) Also in Spanish
- Bile Duct Cancer Diagnosis (National Cancer Institute) Also in Spanish
- Bilirubin Blood Test (National Library of Medicine) Also in Spanish
- Endoscopic Retrograde Cholangiopancreatography (ERCP) (National Institute of Diabetes and Digestive and Kidney Diseases) Also in Spanish
- Tests for Bile Duct Cancer (American Cancer Society)
Prevention and Risk Factors
- Bile Duct Cancer Causes and Risk Factors (National Cancer Institute) Also in Spanish
Treatments and Therapies
- Bile Duct Cancer Treatment (National Cancer Institute) Also in Spanish
- Endoscopic retrograde cholangio pancreatography (ERCP) - series (Medical Encyclopedia) Also in Spanish
- Radiation Therapy for Bile Duct Cancer (American Cancer Society)
- Surgery for Bile Duct Cancer (American Cancer Society)
Living With
- Living as a Bile Duct Cancer Survivor (American Cancer Society)
Related Issues
- Bile Duct Risk Factors (American Cancer Society)
- What Causes Bile Duct Cancer? (American Cancer Society)
Specifics
- Bile Duct Cancer Stages (National Cancer Institute) Also in Spanish
Genetics
- Cholangiocarcinoma: MedlinePlus Genetics (National Library of Medicine)
Statistics and Research
- Cancer Statistics: Liver and Intrahepatic Bile Duct Cancer (National Cancer Institute)
- Key Statistics for Bile Duct Cancer (American Cancer Society)
Clinical Trials
- ClinicalTrials.gov: Bile Duct Neoplasms (National Institutes of Health)
- ClinicalTrials.gov: Cholangiocarcinoma (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Impact of Clinical Characteristics and Treatment on Cholangiocarcinoma Prognosis in Southern...
- Article: Differential circulating miRNA profiles identified miR-423-5p, miR-93-5p, and miR-4532 as potential...
- Article: Comparison of lenvatinib plus pembrolizumab versus first-line systemic chemotherapy for advanced...
- Bile Duct Cancer -- see more articles
Find an Expert
- American Cancer Society
- ASGE: Find a Doctor (American Society for Gastrointestinal Endoscopy)
- Choosing a Cancer Doctor (American Cancer Society) Also in Spanish
- Find a Gastroenterologist (American College of Gastroenterology)
- National Cancer Institute Also in Spanish
- National Institute of Diabetes and Digestive and Kidney Diseases
- Organizations that Offer Cancer Support Services (National Cancer Institute) Also in Spanish
Patient Handouts
- Bile duct stricture (Medical Encyclopedia) Also in Spanish
- Cholangiocarcinoma (Medical Encyclopedia) Also in Spanish
- ERCP (Medical Encyclopedia) Also in Spanish