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Aceite de Palma

¿Qué es?

El aceite de palma se obtiene del fruto del aceite de la palma.

El aceite de palma se utiliza para prevenir la deficiencia de vitamina, el cáncer, la enfermedad cerebral y el envejecimiento. También se lo usa para para el tratamiento del paludismo, de la presión arterial alta, del colesterol alto, de la demencia y de la intoxicación por cianuro. El aceite de palma se usa para perder peso y para acelerar el metabolismo del cuerpo.

Como alimento, el aceite de palma se utiliza para freír. También se lo usa como ingredientes en muchos alimentos procesados.

En la industria, el aceite de palma se utiliza para la fabricación de cosméticos, jabones, pasta de dientes, ceras, lubricantes y tinta.

¿Qué tan efectivo es?

Natural Medicines Comprehensive Database (La Base Exhaustiva de Datos de Medicamentos Naturales) clasifica la eficacia, basada en evidencia científica, de acuerdo a la siguiente escala: Eficaz, Probablemente Eficaz, Posiblemente Eficaz, Posiblemente Ineficaz, Probablemente Ineficaz, Ineficaz, e Insuficiente Evidencia para Hacer una Determinación.

La clasificación de la eficacia para este producto es la siguiente:

Posiblemente eficaz para...

  • Prevenir o tratar la falta de vitamina A (deficiencia de vitamina A). Existe cierta evidencia que indica que la adición de un tipo especial de aceite de palma roja a la dieta de las mujeres embarazadas y de los niños en los países en desarrollo reduce el riesgo de tener deficiencia de vitamina A. Existe también cierta evidencia de que agregar este mismo aceite en las dietas de mujeres embarazadas y niños que ya tienen carencia de vitamina A puede reemplazar la carencia de vitamina A.

Insuficiente evidencia para hacer una determinación para...

  • Paludismo. Cierta investigación sugiere que la ingesta de aceite de palma en la dieta no parece disminuir los síntomas del paludismo en niños menores de 5 años en países en desarrollo.
  • Antienvejecimiento.
  • Enfermedad cerebral.
  • Cáncer.
  • Intoxicación por cianuro.
  • Presión arterial alta.
  • Agente para la pérdida de peso.
  • Otras condiciones.
Se necesitan más pruebas para evaluar la eficacia del aceite de palma para estos usos.

¿Cómo funciona?

El aceite de palma contiene grasas saturadas y no saturadas. Algunos tipos de aceite de palma contienen vitamina E y betacarteno. Estos tipos de aceite de palma podrían tener efectos antioxidantes.

¿Hay preocupación por la seguridad de su uso?

El aceite de palma ES PROBABLEMENTE SEGURO cuando se ingiere en cantidades presentes en los alimentos. No obstante, el aceite de palma contiene un tipo de grasa que puede aumentar los niveles de colesterol. Por esto, se debería evitar comer aceite de palma en exceso. El aceite de palma ES POSIBLEMENTE SEGURO cuando se usa como medicina por tiempo breve. La ingesta diaria de 9-12 gramos diarios durante un máximo de 6 meses parece ser seguro.

Advertencias y precauciones especiales:

Embarazo y lactancia: El aceite de palma ES POSIBLEMENTE SEGURO cuando se usa como medicina durante los últimos 3 meses del embarazo. No se conoce suficiente sobre el uso del aceite de palma como medicamento durante la lactancia. Sea precavida y consuma las cantidades presentes en los alimentos.

Niños: El aceite de palma ES POSIBLEMENTE SEGURO cuando se ingiere como medicina. El aceite de palma ha sido usado durante un máximo de 6 meses en niños menores de 5 años y durante un máximo de que meses en niños desde 5 años en adelante.

Colesterol alto: El aceite de palma contiene un tipo de grasa que puede aumentar los niveles de colesterol. Ingerir alimentos que contienen aceite de palma de manera regular puede aumentar los niveles de colesterol de lipoproteína de baja densidad o colesterol «malo». Esto podría representar un problema en personas que ya tienen altos niveles de colesterol.

¿Existen interacciones con medicamentos?

Moderadas
Tenga cuidado con esta combinación
Los medicamentos que disminuyen la coagulación de la sangre (Fármacos anticoagulantes/antiplaquetarios)
El aceite de palma podría aumentar la coagulación sanguínea. El tomar aceite de palma junto con medicamentos que disminuyen la coagulación podría reducir la efectividad de estos medicamentos.

Algunos medicamentos que retardan la coagulación sanguínea incluyen aspirina, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, otros), ibuprofeno (Advil, Motrin y otros), naproxeno (Anaprox, Naprosyn, otros), dalteparina (Fragmin), enoxaparina (Lovenox) heparina, warfarina (Coumadin) y otros.

¿Existen interacciones con hierbas y suplementos?

:
:

¿Existen interacciones con alimentos?

No se conoce ninguna interacción con alimentos.

¿Qué dosis se utiliza?

La siguientes dosis se han estudiado en investigación científica:

ADULTOS
POR BOCA:
  • Para la prevención o tratamiento de la deficiencia de vitamina A: Se usó cerca de 4 cucharadas (12 gramos) de aceite de palma roja por día.
NIÑOS
POR BOCA
  • Para la prevención o tratamiento de la deficiencia de vitamina A: Se usó cerca de 3 cucharadas (9 gramos) de aceite de palma roja por día en niños mayores de 5 años. Se usó 2 cucharadas (12 gramos) de aceite de palma roja por día en niños menores de 5 años.

Otros nombres

Aceite de Palma, African Palm Oil, Crude Palm Oil, Elaeis guineensis, Elaeis melanococca, Elaeis oleifera, Huile de Palme, Huile de Palme Brute, Huile de Palme Rouge, Huile de Palmiste, Oil Palm Tree, Palm, Palm Fruit Oil, Palm Kernel Oil, Palm Oil Carotene, Palmier à Huile, Red Palm Oil, Virgin Palm Oil.

Metodología

Para saber más sobre cómo este artículo fue escrito, refiérase a la metodología de la Base exhaustiva de datos de medicamentos naturales.

Referencias

  1. Dong S, Xia H, Wang F, Sun G. The Effect of Red Palm Oil on Vitamin A Deficiency: A Meta-Analysis of Randomized Controlled Trials. Nutrients. 2017;9. View abstract.
  2. Beshel FN, Antai AB, Osim EE. Chronic consumption of three forms of palm oil diets alters glomerular filtration rate and renal plasma flow. Gen Physiol Biophys. 2014;33:251-6. doi: 10.4149/gpb_2013069. Epub 2013 Oct 31. View abstract.
  3. Chen BK, Seligman B, Farquhar JW, Goldhaber-Fiebert JD. Multi-Country analysis of palm oil consumption and cardiovascular disease mortality for countries at different stages of economic development: 1980-1997. Global Health 2011;7:45. View abstract.
  4. Sun Y, Neelakantan N, Wu Y, et al. Palm oil consumption increases LDL cholesterol compared with vegetable oils low in saturated fat in a meta-analysis of clinical trials. J Nutr 2015;145:1549-58. View abstract.
  5. Akanda MJ, Sarker MZ, Ferdosh S, et al. Applications of supercritical fluid extraction (SFE) of palm oil and oil from natural sources. Molecules 2012;17:1764-94. View abstract.
  6. Lucci P, Borrero M, Ruiz A, et al. Palm oil and cardiovascular disease: a randomized trial of the effects of hybrid palm oil supplementation on human plasma lipid patterns. Food Funct 2016;7:347-54. View abstract.
  7. Fattore E, Bosetti C, Brighenti F, et al. Palm oil and blood lipid-related markers of cardiovascular disease: a systematic review and meta-analysis of dietary intervention trials. Am J Clin Nutr 2014;99:1331-50. View abstract.
  8. Pletcher, J. Public interventions in agricultural markets in Malaysia: rice and palm oil. Modern Asian Studies 1990;24:323-340.
  9. Hinds, E. A. Government policy and the Nigerian palm oil export industry, 1939-49. Journal of African History 1997;38:459-478.
  10. Lynn, M. The profitability of the early Nineteenth Century palm oil trade. African Economic History 1992;20:77-97.
  11. Khosla, P. and Hayes, K. C. Pa
  12. Sundram, K., Hayes, K. C., and Siru, O. H. Both dietary 18:2 and 16:0 may be required to improve the serum LDL/HDL cholesterol ratio in normocholesterolemic men. Journal of Nutritional Biochemistry 1995;6:179-187.
  13. Melo, M. D. and Mancini, J. Natural antioxidants from palm fruit (Elaeis guineensis, Jacq). Revista de Farmacia e Bioquimica da Universidade de Sao Paulo (Brazil) 1989;258:147-157.
  14. Kooyenga, D. K., Geller, M., Watkins, T. R., Gapor, A., Diakoumakis, E., and Bierenbaum, M. L. Palm oil antioxidant effects in patients with hyperlipidaemia and carotid stenosis-2 year experience. Asia Pac.J Clin.Nutr. 1997;6:72-75.
  15. Oluba, O. M., Onyeneke, C. E., Ojien, G. C., Eidangbe, G. O., and Orole, R. T. Effects of palm oil supplementation on lipid peroxidation and glutathione peroxidase activity in cholesterol-fed rats. The Internet Journal of Cardiovascular Research 2009;6
  16. Heber, D., Ashley, J. M., Solares, M. E., and Wang, J. H. The effects of a palm-oil enriched diet on plasma lipids and lipoproteins in healthy young men. Nutrition Research 1992;12(Suppl 1):S53-S59.
  17. Mutalib, M. S. A., Wahle, K. W. J., Duthie, G. G., Whiting, P., Peace, H., and Jenkinson, A. Human Studies-The Effect of Dietary Palm Oil, Hydrogenated Rape and Soya Oil on indices of Coronary Heart Disease Risk in Healthy Scottish Volunteers. Nutrition Research 1999;19:335.
  18. Narasinga Rao, B. S. Potential use of red palm oil in combating vitamin A deficiency in India. Food & Nutrition Bulletin 2000;21:202-211.
  19. van Stuijvenberg, M. E. and Benade, A. J. S. South African experience with the use of red palm oil to improve the vitamin A status of primary school children. Food & Nutrition Bulletin 2000;21:212-221.
  20. Anderson, J. T., Grande, F., and Keys, A. Independence of the effects of cholesterol and degree of saturation of the fat in the diet on serum cholesterol in man. Am J Clin Nutr 1976;29:1184-1189. View abstract.
  21. Solomons, N. W. Plant sources of vitamin A and human nutrition: red palm oil does the job. Nutr.Rev 1998;56:309-311. View abstract.
  22. Muller, H., Jordal, O., Kierulf, P., Kirkhus, B., and Pedersen, J. I. Replacement of partially hydrogenated soybean oil by palm oil in margarine without unfavorable effects on serum lipoproteins. Lipids 1998;33:879-887. View abstract.
  23. Gouado, I., Mbiapo, T. F., Moundipa, F. P., and Teugwa, M. C. Vitamin A and E status of some rural populations in the north of Cameroon. Int J Vitam.Nutr Res 1998;68:21-25. View abstract.
  24. Manorama, R., Brahmam, G. N., and Rukmini, C. Red palm oil as a source of beta-carotene for combating vitamin A deficiency. Plant Foods Hum.Nutr. 1996;49:75-82. View abstract.
  25. Zhang, J., Ping, W., Chunrong, W., Shou, C. X., and Keyou, G. Nonhypercholesterolemic effects of a palm oil diet in Chinese adults. J Nutr. 1997;127:509S-513S. View abstract.
  26. Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr. 1997;65:41-45. View abstract.
  27. de Bosch, N. B., Bosch, V., and Apitz, R. Dietary fatty acids in athero-thrombogenesis: influence of palm oil ingestion. Haemostasis 1996;26 Suppl 4:46-54. View abstract.
  28. Enas, E. A. Cooking oils, cholesterol and CAD: facts and myths. Indian Heart J 1996;48:423-427. View abstract.
  29. Zock, P. L., Gerritsen, J., and Katan, M. B. Partial conservation of the sn-2 position of dietary triglycerides in fasting plasma lipids in humans. Eur J Clin Invest 1996;26:141-150. View abstract.
  30. Zock, P. L., de Vries, J. H., and Katan, M. B. Impact of myristic acid versus palmitic acid on serum lipid and lipoprotein levels in healthy women and men. Arterioscler.Thromb. 1994;14:567-575. View abstract.
  31. Sundram, K., Hayes, K. C., and Siru, O. H. Dietary palmitic acid results in lower serum cholesterol than does a lauric-myristic acid combination in normolipemic humans. Am J Clin Nutr 1994;59:841-846. View abstract.
  32. Tholstrup, T., Marckmann, P., Jespersen, J., Vessby, B., Jart, A., and Sandstrom, B. Effect on blood lipids, coagulation, and fibrinolysis of a fat high in myristic acid and a fat high in palmitic acid. Am J Clin Nutr 1994;60:919-925. View abstract.
  33. Grange, A. O., Santosham, M., Ayodele, A. K., Lesi, F. E., Stallings, R. Y., and Brown, K. H. Evaluation of a maize-cowpea-palm oil diet for the dietary management of Nigerian children with acute, watery diarrhea. Acta Paediatr. 1994;83:825-832. View abstract.
  34. Pronczuk, A., Khosla, P., and Hayes, K. C. Dietary myristic, palmitic, and linoleic acids modulate cholesterolemia in gerbils. FASEB J 1994;8:1191-1200. View abstract.
  35. Schwab, U. S., Niskanen, L. K., Maliranta, H. M., Savolainen, M. J., Kesaniemi, Y. A., and Uusitupa, M. I. Lauric and palmitic acid-enriched diets have minimal impact on serum lipid and lipoprotein concentrations and glucose metabolism in healthy young women. J Nutr 1995;125:466-473. View abstract.
  36. Wardlaw, G. M., Snook, J. T., Park, S., Patel, P. K., Pendley, F. C., Lee, M. S., and Jandacek, R. J. Relative effects on serum lipids and apolipoproteins of a caprenin-rich diet compared with diets rich in palm oil/palm-kernel oil or butter. Am.J Clin.Nutr. 1995;61:535-542. View abstract.
  37. Zock, P. L., de Vries, J. H., de Fouw, N. J., and Katan, M. B. Positional distribution of fatty acids in dietary triglycerides: effects on fasting blood lipoprotein concentrations in humans. Am J Clin Nutr 1995;61:48-55. View abstract.
  38. Lai, H. C. and Ney, D. M. Corn oil, palm oil and butterfat fractions affect postprandial lipemia and lipoprotein lipase in meal-fed rats. J Nutr 1995;125:1536-1545. View abstract.
  39. Dougherty, R. M., Allman, M. A., and Iacono, J. M. Effects of diets containing high or low amounts of stearic acid on plasma lipoprotein fractions and fecal fatty acid excretion of men. Am J Clin Nutr 1995;61:1120-1128. View abstract.
  40. Choudhury, N., Tan, L., and Truswell, A. S. Comparison of palmolein and olive oil: effects on plasma lipids and vitamin E in young adults. Am J Clin Nutr 1995;61:1043-1051. View abstract.
  41. Nestel, P. J., Noakes, M., Belling, G. B., McArthur, R., and Clifton, P. M. Effect on plasma lipids of interesterifying a mix of edible oils. Am J Clin Nutr 1995;62:950-955. View abstract.
  42. Binns, C. W., Pust, R. E., and Weinhold, D. W. Palm oil: a pilot study of its use in a nutrition intervention programme. J Trop.Pediatr. 1984;30:272-274. View abstract.
  43. Stack, K. M., Churchwell, M. A., and Skinner, R. B., Jr. Xanthoderma: case report and differential diagnosis. Cutis 1988;41:100-102. View abstract.
  44. Khosla, P. and Hayes, K. C. Dietary fat saturation in rhesus monkeys affects LDL concentrations by modulating the independent production of LDL apolipoprotein B. Biochim.Biophys.Acta 4-24-1991;1083:46-56. View abstract.
  45. Cottrell, R. C. Introduction: nutritional aspects of palm oil. Am.J Clin.Nutr. 1991;53(4 Suppl):989S-1009S. View abstract.
  46. Ng, T. K., Hassan, K., Lim, J. B., Lye, M. S., and Ishak, R. Nonhypercholesterolemic effects of a palm-oil diet in Malaysian volunteers. Am J Clin Nutr 1991;53(4 Suppl):1015S-1020S. View abstract.
  47. Adam, S. K., Das, S., and Jaarin, K. A detailed microscopic study of the changes in the aorta of experimental model of postmenopausal rats fed with repeatedly heated palm oil. Int J Exp.Pathol. 2009;90:321-327. View abstract.
  48. Utarwuthipong, T., Komindr, S., Pakpeankitvatana, V., Songchitsomboon, S., and Thongmuang, N. Small dense low-density lipoprotein concentration and oxidative susceptibility changes after consumption of soybean oil, rice bran oil, palm oil and mixed rice bran/palm oil in hypercholesterolaemic women. J Int Med Res 2009;37:96-104. View abstract.
  49. Ladeia, A. M., Costa-Matos, E., Barata-Passos, R., and Costa, Guimaraes A. A palm oil-rich diet may reduce serum lipids in healthy young individuals. Nutrition 2008;24:11-15. View abstract.
  50. Berry, S. E., Woodward, R., Yeoh, C., Miller, G. J., and Sanders, T. A. Effect of interesterification of palmitic acid-rich triacylglycerol on postprandial lipid and factor VII response. Lipids 2007;42:315-323. View abstract.
  51. Khosla, P. and Hayes, K. C. Comparison between the effects of dietary saturated (16:0), monounsaturated (18:1), and polyunsaturated (18:2) fatty acids on plasma lipoprotein metabolism in cebus and rhesus monkeys fed cholesterol-free diets. Am J Clin Nutr 1992;55:51-62. View abstract.
  52. Zeba, A. N., Martin, Prevel Y., Some, I. T., and Delisle, H. F. The positive impact of red palm oil in school meals on vitamin A status: study in Burkina Faso. Nutr J 2006;5:17. View abstract.
  53. Vega-Lopez, S., Ausman, L. M., Jalbert, S. M., Erkkila, A. T., and Lichtenstein, A. H. Palm and partially hydrogenated soybean oils adversely alter lipoprotein profiles compared with soybean and canola oils in moderately hyperlipidemic subjects. Am J Clin Nutr 2006;84:54-62. View abstract.
  54. Lietz, G., Mulokozi, G., Henry, J. C., and Tomkins, A. M. Xanthophyll and hydrocarbon carotenoid patterns differ in plasma and breast milk of women supplemented with red palm oil during pregnancy and lactation. J Nutr 2006;136:1821-1827. View abstract.
  55. Pedersen, J. I., Muller, H., Seljeflot, I., and Kirkhus, B. Palm oil versus hydrogenated soybean oil: effects on serum lipids and plasma haemostatic variables. Asia Pac.J Clin Nutr 2005;14:348-357. View abstract.
  56. Ng, T. K., Hayes, K. C., DeWitt, G. F., Jegathesan, M., Satgunasingam, N., Ong, A. S., and Tan, D. Dietary palmitic and oleic acids exert similar effects on serum cholesterol and lipoprotein profiles in normocholesterolemic men and women. J Am Coll.Nutr 1992;11:383-390. View abstract.
  57. Sundram, K., Hornstra, G., von Houwelingen, A. C., and Kester, A. D. Replacement of dietary fat with palm oil: effect on human serum lipids, lipoproteins and apolipoproteins. Br.J Nutr. 1992;68:677-692. View abstract.
  58. Elson, C. E. Tropical oils: nutritional and scientific issues. Crit Rev.Food Sci Nutr 1992;31(1-2):79-102. View abstract.
  59. Bosch, V., Aular, A., Medina, J., Ortiz, N., and Apitz, R. [Changes in of plasma lipoproteins after the use of palm oil in the diet of a group healthy adults]. Arch Latinoam.Nutr 2002;52:145-150. View abstract.
  60. Hallebeek, J. M. and Beynen, A. C. The plasma level of triacylglycerols in horses fed high-fat diets containing either soybean oil or palm oil. J Anim Physiol Anim Nutr (Berl) 2002;86(3-4):111-116. View abstract.
  61. Montoya, M. T., Porres, A., Serrano, S., Fruchart, J. C., Mata, P., Gerique, J. A., and Castro, G. R. Fatty acid saturation of the diet and plasma lipid concentrations, lipoprotein particle concentrations, and cholesterol efflux capacity. Am J Clin Nutr 2002;75:484-491. View abstract.
  62. Schlierf, G., Jessel, S., Ohm, J., Heuck, C. C., Klose, G., Oster, P., Schellenberg, B., and Weizel, A. Acute dietary effects on plasma lipids, lipoproteins and lipolytic enzymes in healthy normal males. Eur J Clin Invest 1979;9:319-325. View abstract.
  63. Sivan, Y. S., Jayakumar, Y. A., Arumughan, C., Sundaresan, A., Balachandran, C., Job, J., Deepa, S. S., Shihina, S. L., Damodaran, M., Soman, C. R., Raman, Kutty, V, and Sankara, Sarma P. Impact of beta-carotene supplementation through red palm. J Trop.Pediatr 2001;47:67-72. View abstract.
  64. Canfield, L. M., Kaminsky, R. G., Taren, D. L., Shaw, E., and Sander, J. K. Red palm oil in the maternal diet increases provitamin A carotenoids in breastmilk and serum of the mother-infant dyad. Eur J Nutr 2001;40:30-38. View abstract.
  65. van Stuijvenberg, M. E., Faber, M., Dhansay, M. A., Lombard, C. J., Vorster, N., and Benade, A. J. Red palm oil as a source of beta-carotene in a school biscuit used to address vitamin A deficiency in primary school children. Int.J.Food Sci.Nutr. 2000;51 Suppl:S43-S50. View abstract.
  66. van Jaarsveld, P. J., Smuts, C. M., Tichelaar, H. Y., Kruger, M., and Benade, A. J. Effect of palm oil on plasma lipoprotein concentrations and plasma low-density lipoprotein composition in non-human primates. Int J Food Sci Nutr. 2000;51 Suppl:S21-S30. View abstract.
  67. Muller, H., Seljeflot, I., Solvoll, K., and Pedersen, J. I. Partially hydrogenated soybean oil reduces postprandial t-PA activity compared with palm oil. Atherosclerosis 2001;155:467-476. View abstract.
  68. Nielsen, N. S., Marckmann, P., and Hoy, C. Effect of meal fat quality on oxidation resistance of postprandial VLDL and LDL particles and plasma triacylglycerol level. Br J Nutr 2000;84:855-863. View abstract.
  69. Cater, N. B. and Denke, M. A. Behenic acid is a cholesterol-raising saturated fatty acid in humans. Am J Clin Nutr 2001;73:41-44. View abstract.
  70. Nestel, P. and Trumbo, P. The role of provitamin A carotenoids in the prevention and control of vitamin A deficiency. Arch Latinoam.Nutr 1999;49(3 Suppl 1):26S-33S. View abstract.
  71. Kritchevsky, D., Tepper, S. A., Chen, S. C., Meijer, G. W., and Krauss, R. M. Cholesterol vehicle in experimental atherosclerosis. 23. Effects of specific synthetic triglycerides. Lipids 2000;35:621-625. View abstract.
  72. Jensen, J., Bysted, A., Dawids, S., Hermansen, K., and Holmer, G. The effect of palm oil, lard, and puff-pastry margarine on postprandial lipid and hormone responses in normal-weight and obese young women. Br.J Nutr. 1999;82:469-479. View abstract.
  73. Ebong, P. E., Owu, D. U., and Isong, E. U. Influence of palm oil (Elaesis guineensis) on health. Plant Foods Hum.Nutr. 1999;53:209-222. View abstract.
  74. Filteau, S. M., Lietz, G., Mulokozi, G., Bilotta, S., Henry, C. J., and Tomkins, A. M. Milk cytokines and subclinical breast inflammation in Tanzanian women: effects of dietary red palm oil or sunflower oil supplementation. Immunology 1999;97:595-600. View abstract.
  75. Cantwell, M. M., Flynn, M. A., and Gibney, M. J. Acute postprandial effect of hydrogenated fish oil, palm oil and lard on plasma cholesterol, triacylglycerol and non-esterified fatty acid metabolism in normocholesterolaemic males. Br J Nutr 2006;95:787-794. View abstract.
  76. Sivan, Y. S., Alwin, Jayakumar Y., Arumughan, C., Sundaresan, A., Jayalekshmy, A., Suja, K. P., Soban Kumar, D. R., Deepa, S. S., Damodaran, M., Soman, C. R., Raman, Kutty, V, and Sankara, Sarma P. Impact of vitamin A supplementation through different dosages of red palm oil and retinol palmitate on preschool children. J.Trop.Pediatr. 2002;48:24-28. View abstract.
  77. van Stuijvenberg, M. E., Dhansay, M. A., Lombard, C. J., Faber, M., and Benade, A. J. The effect of a biscuit with red palm oil as a source of beta-carotene on the vitamin A status of primary school children: a comparison with beta-carotene from a synthetic source in a randomised controlled trial. Eur.J.Clin.Nutr. 2001;55:657-662. View abstract.
  78. Wilson TA, Nicolosi RJ, Kotyla T, et al. Different oil preparations reduce plasma cholesterol concentrations and aortic cholesterol accumulation compared to coconut oil in hypercholesterolemic hamsters. J Biochem 2005;16:633-40. View abstract.
  79. Bester DJ, van Rooyen J, du Toit EF, et al. Red palm oil protects against the consequences of oxidative stress when supplemented with dislipidemic diets. Med Tech SA 2006;20:3-10.
  80. Esterhuyse AJ, du Toit EF, Benade AJS, et al. Dietary red palm oil improves reperfusion cardiac function in the isolated perfused rat heart of animals fed a high cholesterol diet. Prostaglandins Leukot Essent Fatty Acids 2005;72:153-61. View abstract.
  81. Esterhuyse JS, van Rooyen J, Strijdom H, et al. Proposed mechanisms for red palm oil-induced cardioprotection in a model of hyperlipidemia in the rat. Prostaglandins Leukot Essent Fatty Acids 2006;75:375-84. View abstract.
  82. Oguntibeju OO, Esterhuyse AJ, Truter EJ. Red palm oil: nutritional, physiological and therapeutic role in improving human wellbeing and quality of life. Br J Biomed Sci 2009;66:216-22. View abstract.
  83. Tholstrup T, Marckmann P, Jespersen J, Sandstrom B. Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids. Am J Clin Nutr 1994;59:371-7. View abstract.
  84. Denke MA, Grundy SM. Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. Am J Clin Nutr 1992;56:895-8. View abstract.
  85. Olmedilla B, Granado F, Southon S, et al. A European multicentre, placebo-controlled supplementation study with alpha-tocopherol, carotene-rich palm oil, lutein or lycopene: analysis of serum responses. Clin Sci (Lond) 2002;102:447-56. View abstract.
  86. Ng MH, Choo YM, Ma AN, et al. Separation of vitamin E (tocopherol, tocotrienol, tocomonoenol) in palm oil. Lipids 2004;39:1031-5. View abstract.
  87. Soelaiman IN, Ahmad NS, Khalid BA. Palm oil tocotrienol mixture is better than alpha-tocopherol acetate in protecting bones against free-radical induced elevation of bone-resorbing cytokines. Asia Pac J Clin Nutr 2004;13:S111. View abstract.
  88. Tiahou G, Maire B, Dupuy A, et al. Lack of oxidative stress in a selenium deficient area in Ivory Coast--potential nutritional antioxidant role of crude palm oil. Eur J Nutr 2004;43:367-74. View abstract.
  89. Agarwal MK, Agarwal ML, Athar M, Gupta S. Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association. Cell Cycle 2004;3;205-11. View abstract.
  90. Nesaretnam K, Ambra R, Selvaduray KR, et al. Tocotrienol-rich fraction from palm oil and gene expression in human breast cancer cells. Ann N Y Acad Sci 2004;1031:143-57. View abstract.
  91. Nesaretnam K, Ambra R, Selvaduray KR, et al. Tocotrienol-rich fraction from palm oil affects gene expression in tumors resulting from MCF-7 cell inoculation in athymic mice. Lipids 2004;39:459-67. View abstract.
  92. Nafeeza MI, Fauzee AM, Kamsiah J, Gapor MT. Comparative effects of a tocotrienol-rich fraction and tocopherol in aspirin-induced gastric lesions in rats. Asia Pac J Clin Nutr 2002;11:309-13. View abstract.
  93. Nesaretnam K, Radhakrishnan A, Selvaduray KR, et al. Effect of palm oil carotene on breast cancer tumorigenicity in nude mice. Lipids 2002;37:557-60. View abstract.
  94. Ghosh S, An D, Pulinilkunnil T, et al. Role of dietary fatty acids and acute hyperglycemia in modulating cardiac cell death. Nutrition 2004;20:916-23. View abstract.
  95. Jaarin K, Gapor MT, Nafeeza MI, Fauzee AM. Effect of various doses of palm vitamin E and tocopherol on aspirin-induced gastric lesions in rats. Int J Exp Pathol 2002;83:295-302. View abstract.
  96. Esterhuyse AJ, du Toit EF, Benade AJ, van Rooyen J. Dietary red palm oil improves reperfusion cardiac function in the isolated perfused rat heart of animals fed a high cholesterol diet. Prostaglandins Leukot Essent Fatty Acids 2005;72:153-61. View abstract.
  97. Narang D, Sood S, Thomas MK, et al. Effect of dietary palm olein oil on oxidative stress associated with ischemic-reperfusion injury in isolated rat heart. BMC Pharmacol 2004;4:29. View abstract.
  98. Aguila MB, Sa Silva SP, Pinheiro AR, Mandarim-de-Lacerda CA. Effects of long-term intake of edible oils on hypertension and myocardial and aortic remodelling in spontaneously hypertensive rats. J Hypertens 2004;22:921-9. View abstract.
  99. Aguila MB, Pinheiro AR, Mandarim-de-Lacerda CA. Spontaneously hypertensive rats left ventricular cardiomyocyte loss attenuation through different edible oils long-term intake. Int J Cardiol 2005;100:461-6. View abstract.
  100. Ganafa AA, Socci RR, Eatman D, et al. Effect of palm oil on oxidative stress-induced hypertension in Sprague-Dawley rats. Am J Hypertens 2002;15:725-31. View abstract.
  101. Sanchez-Muniz FJ, Oubina P, Rodenas S, et al. Platelet aggregation, thromboxane production and thrombogenic ratio in postmenopausal women consuming high oleic acid-sunflower oil or palmolein. Eur J Nutr 2003:42:299-306. View abstract.
  102. Kritchevsky D, Tepper SA, Czarnecki SK, Sundram K. Red palm oil in experimental atherosclerosis. Asia Pac J Clin Nutr 2002;11:S433-7. View abstract.
  103. Jackson KG, Wolstencroft EJ, Bateman PA, et al. Greater enrichment of triacylglycerol-rich lipoproteins with apolipoproteins E and C-III after meals rich in saturated fatty acids than after meals rich in unsaturated fatty acids. Am J Clin Nutr 2005;81:25-34. View abstract.
  104. Cooper KA, Adelekan DA, Esimai AO, et al. Lack of influence of red palm oil on severity of malaria infection in pre-school Nigerian children. Trans R Soc Trop Med Hyg 2002;96;216-23. View abstract.
  105. Clandinin MT, Larsen B, Van Aerde J. Reduced bone mineralization in infants fed palm olein-containing formula: a randomized, double-blinded, prospective trial. Pediatrics 2004;114:899-900. View abstract.
  106. Lietz G, Henry CJ, Mulokozi G, et al. Comparison of the effects of supplemental red palm oil and sunflower oil on maternal vitamin A status. Am J Clin Nutr 2001;74:501-9. View abstract.
  107. Zagre NM, Delpeuch F, Traissac P, Delisle H. Red palm oil as a source of vitamin A for mothers and children: impact of a pilot project in Burkina Faso. Public Health Nutr 2003;6:733-42. View abstract.
  108. Radhika MS, Bhaskaram P, Balakrishna N, Ramalakshmi BA. Red palm oil supplementation: a feasible diet-based approach to improve vitamin A status of pregnant women and their infants. Food Nutr Bull 2003;24:208-17. View abstract.
  109. Scholtz SC, Pieters M, Oosthuizen W, et al. The effect of red palm olein and refined palm olein on lipids and haemostatic factors in hyperfibrinogenaemic subjects. Thromb Res 2004;113:13-25. View abstract.
  110. Zhang J, Wang CR, Xue AN, Ge KY. Effects of red palm oil on serum lipids and plasma carotenoids level in Chinese male adults. Biomed Environ Sci 2003;16:348-54. View abstract.
  111. Bautista LE, Herran OF, Serrano C. Effects of palm oil and dietary cholesterol on plasma lipoproteins: results from a dietary crossover trial in free-living subjects. Eur J Clin Nutr 2001;55:748-54. View abstract.
  112. Solomons NW, Orozco M. Alleviation of vitamin A deficiency with palm fruit and its products. Asia Pac J Clin Nutr 2003;12:373-84. View abstract.
  113. Benade AJ. A place for palm fruit oil to eliminate vitamin A deficiency. Asia Pac J Clin Nutr 2003;12:369-72. View abstract.
  114. Sundram K, Sambanthamurthi R, Tan YA. Palm fruit chemistry and nutrition. Asia Pac J Clin Nutr 2003;12:369-72. View abstract.
  115. Wattanapenpaiboon N, Wahlqvist MW. Phytonutrient deficiency: the place of palm fruit. Asia Pac J Clin Nutr 2003;12:363-8. View abstract.
  116. Atinmo T, Bakre AT. Palm fruit in traditional African food culture. Asia Pac J Clin Nutr 2003;12:350-4. View abstract.
  117. Ong AS, Goh SH. Palm oil: a healthful and cost-effective dietary component. Food Nutr Bull 2002;23;11-22. View abstract.
  118. Edem DO. Palm oil: biochemical, physiological, nutritional, hematological, and toxicological aspects: a review. Plant Foods Hum Nutr 2002;57:319-41. View abstract.
  119. Tomeo AC, Geller M, Watkins TR, et al. Antioxidant effects of tocotrienols in patients with hyperlipidemia and carotid stenosis. Lipids 1995;30:1179-83. View abstract.
  120. Qureshi AA, Qureshi N, Wright JJ, et al. Lowering of serum cholesterol in hypercholesterolemic humans by tocotrienols (palmvitee). Am J Clin Nutr 1991;53:1021S-6S. View abstract.
Documento revisado - 12/06/2018