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Summary
The tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma, also known as malignant mesothelioma, is cancer of that tissue. It usually starts in the lungs, but can also start in the abdomen or other organs.
Malignant mesothelioma is rare but serious. Most people who get it have worked or lived in places where they inhaled or swallowed asbestos particles. After being exposed to asbestos, it usually takes a long time for the disease to form.
Symptoms include:
- Trouble breathing
- Cough
- Pain under the rib cage
- Pain, swelling, or lumps in the abdomen
- Weight loss for no known reason
- Blood clots
- Constipation
- Fatigue
Sometimes it is hard to tell the difference between malignant mesothelioma and lung cancer. To find out if you have mesothelioma, your health care provider will likely use a physical exam, imaging tests, and a biopsy.
Malignant mesothelioma is often found when it is advanced. This makes it harder to treat. Treatment options may include:
- Surgery
- Radiation therapy
- Chemotherapy
- Immunotherapy
- Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells
NIH: National Cancer Institute
Diagnosis and Tests
- Early Detection, Diagnosis, and Staging of Mesothelioma (American Cancer Society)
-
Stages of Malignant Mesothelioma
(National Cancer Institute)
Also in Spanish
Prevention and Risk Factors
- Causes, Risk Factors, and Prevention of Mesothelioma (American Cancer Society)
- Learn about Mesothelioma (American Lung Association)
Treatments and Therapies
-
Drugs Approved for Malignant Mesothelioma
(National Cancer Institute)
-
Treatment Option Overview (Malignant Mesothelioma)
(National Cancer Institute)
Also in Spanish
Related Issues
-
Asbestos Exposure and Cancer Risk
(National Cancer Institute)
Also in Spanish
Statistics and Research
- Key Statistics about Malignant Mesothelioma (American Cancer Society)
Clinical Trials
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ClinicalTrials.gov: Mesothelioma
(National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition...
- Article: Surveillance of Non-Malignant Asbestos-Related Diseases in an Exposed Population: A Scoping...
- Article: SATB2 Induces Malignant Transformation and Cancer Stem Cell Characteristics, and Inhibition...
- Mesothelioma -- see more articles
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Children
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Childhood Mesothelioma Treatment
(National Cancer Institute)
Also in Spanish
Patient Handouts
- Malignant mesothelioma (Medical Encyclopedia) Also in Spanish
- Solitary fibrous tumor (Medical Encyclopedia) Also in Spanish