Kawasaki disease is a rare childhood disease. It makes the walls of the blood vessels in the body become inflamed. It can affect any type of blood vessel, including the arteries, veins, and capillaries.
No one knows what causes Kawasaki disease. Symptoms include
- High fever that lasts longer than 5 days
- Swollen lymph nodes in the neck
- A rash on the mid-section and genital area
- Red, dry, cracked lips and a red, swollen tongue
- Red, swollen palms of the hands and soles of the feet
- Redness of the eyes
Kawasaki disease can't be passed from one child to another. There is no single test. To diagnose it, doctors look at the signs and symptoms. They may also use an echocardiogram or other tests. It is mainly treated with medicines. Rarely, medical procedures and surgery also may be used for children whose coronary arteries are affected.
Kawasaki disease can't be prevented. However, most children who develop the disease fully recover - usually within weeks of getting signs and symptoms. Further problems are rare.
NIH: National Heart, Lung, and Blood Institute
Treatments and Therapies
- Kawasaki Disease: Complications, Treatment and Prevention (American Heart Association)
- What is Vasculitis? (National Heart, Lung, and Blood Institute)
- Genetics Home Reference: Kawasaki disease (National Library of Medicine)
- ClinicalTrials.gov: Mucocutaneous Lymph Node Syndrome (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Polymorphisms in endothelial protein C receptor gene and Kawasaki disease susceptibility...
- Article: TNF-α blockers for the treatment of Kawasaki disease in children.
- Article: Tumor necrosis factor-α-308 polymorphism is not associated with Kawasaki disease: A...
- Kawasaki Disease -- see more articles