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When the carotid arteries become blocked with cholesterol plaques (atherosclerotic plaques), blood flow to the brain is compromised. Also, small pieces of plaque can break off and block small arteries in the brain. This blockage of the blood vessels can cause transient-ischemic attacks and strokes.
Review Date 5/5/2025
Updated by: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.