Mycoplasma pneumonia

Mycoplasma pneumonia usually affects people younger than 40.

People who live or work in crowded areas such as schools and homeless shelters have a high chance of getting this condition. But many people who get sick with it have no known risk factors.

Symptoms are often mild and appear over 1 to 3 weeks. They may become more severe in some people.

Common symptoms include any of the following:

• Chest pain
• Chills
• Cough, usually dry and not bloody
• Excessive sweating
• Fever (may be high)
• Headache
• Sore throat

Less common symptoms include:

• Ear pain
• Eye pain or soreness
• Muscle aches and joint stiffness
• Neck lump
• Rapid breathing
• Skin lesions or rash

People with suspected pneumonia should have a complete medical evaluation. It may be hard for your health care provider to tell whether you have pneumonia, bronchitis, or another respiratory infection, so you may need a chest x-ray.

Depending on how severe your symptoms are, other tests may be done, including:

• Complete blood count (CBC)
• Blood tests
• Bronchoscopy (rarely needed)
• CT scan of the chest
• Measuring levels of oxygen and carbon dioxide in the blood (arterial blood gases)
• Nose or throat swab to check for bacteria and viruses
• Open lung biopsy (only done in very serious illnesses when the diagnosis cannot be made from other sources, so very rarely needed)
• Sputum tests to check for mycoplasma bacteria

In many cases, it is not necessary to make the specific diagnosis before starting treatment.

To feel better, you can take these self-care measures at home:

• Control your fever with aspirin, NSAIDs (such as ibuprofen or naproxen), or acetaminophen. DO NOT give aspirin to children because it may cause a dangerous illness called Reye syndrome.
• Do not take cough medicines without first talking to your provider. Cough medicines may make it harder for your body to cough up the extra sputum.
• Drink plenty of fluids to help loosen secretions and bring up phlegm.
• Get a lot of rest. Have someone else do household chores.

Antibiotics are used to treat atypical pneumonia:

• You may be able to take antibiotics by mouth at home.
• If your condition is severe, you will likely be admitted to a hospital. There, you will be given antibiotics through a vein (intravenously), as well as oxygen.
• Antibiotics might be used for 2 weeks or more, although usually fewer days are needed.
• Finish all the antibiotics you've been prescribed, even if you feel better. If you stop the medicine too soon, the pneumonia can return and may be harder to treat.

Most people recover completely without antibiotics, although antibiotics may speed recovery. In untreated adults, cough and weakness can last for up to a month. The disease can be more serious in older adults and in those with a weakened immune system.

Complications that may result include any of the following:

• Ear infections
• Hemolytic anemia, a condition in which there are not enough red blood cells in the blood because the body is destroying them
• Skin rashes

Contact your provider if you develop a fever, cough, or shortness of breath. There are many causes for these symptoms. The provider will need to rule out pneumonia.

Also, call if you have been diagnosed with this type of pneumonia and your symptoms become worse after improving first.

Wash your hands often, and have other people around you do the same.

Avoid contact with other sick people.

If your immune system is weak, stay away from crowds. Ask visitors who have a cold to wear a mask.

Do not smoke. If you do, get help to quit.

Get a flu shot every year. Ask your provider if you need a pneumonia vaccine.

Walking pneumonia; Community-acquired pneumonia - mycoplasma; Community-acquired pneumonia - atypical

Baum SG, Goldman DL. Mycoplasma infections. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 301.

Dockrell DH, Ho A, Gordon SB. Community-acquired pneumonia. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 46.

Holzman RS, Simberkoff MS, Leaf HL. Mycoplasma pneumoniae and atypical pneumonia. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 183.

Updated by: Denis Hadjiliadis, MD, MHS, Paul F. Harron Jr. Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.