Hops

There is interest in using hops for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.

Special precautions & warnings:

Moderate

Be cautious with this combination.

Estrogens

Hops might have some of the same effects as estrogen. Taking hops along with estrogen might decrease the effects of estrogen.

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)

Some medications are changed and broken down by the liver. Hops might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)

Some medications are changed and broken down by the liver. Hops might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Sedative medications (CNS depressants)

Hops might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking hops with sedative medications might cause breathing problems and/or too much sleepiness.

Herbs and supplements with sedative properties

Hops might cause sleepiness and slowed breathing. Taking it along with other supplements with similar effects might cause too much sleepiness and/or slowed breathing in some people. Examples of supplements with this effect include kava, L-tryptophan, melatonin, and valerian.

Herbs that might act like estrogen

Hops might have the same effects as estrogen. Using it along with other supplements with similar effects might increase estrogen-like effects and side effects. Examples of supplements with this effect include black cohosh, kudzu, peony, and red clover.

There are no known interactions with foods.

To learn more about how this article was written, please see the Natural Medicines Comprehensive Database methodology.

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