What is it?
Oats might reduce cholesterol and blood sugar levels, and help control appetite by making you feel full. Oat bran might work by keeping the gut from absorbing substances that can lead to heart disease, high cholesterol, and diabetes. Oats seem to reduce swelling when applied to the skin.
Oat bran and whole oats are used for heart disease, high cholesterol, and diabetes. They are also used for high blood pressure, cancer, dry skin, and many other conditions, but there is no good scientific evidence to support these other uses.
How effective is it?
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
The effectiveness ratings for OATS are as follows:
Likely effective for...
- Heart disease. Oats contain fiber. Eating a diet high in fiber, such as 3.6 grams of oats daily, reduces the risk for heart disease.
- High cholesterol. Eating oats, oat bran, and other soluble fibers can somewhat reduce total and low-density lipoprotein (LDL or "bad") cholesterol when consumed as part of a diet low in saturated fat.
Possibly effective for...
- Diabetes. Eating a diet rich in whole grains, including oats and oat bran, might help prevent diabetes. It might also help improve blood sugar control and lower cholesterol levels in people with diabetes.
- Stomach cancer. Eating high-fiber foods, such as oats and oat bran, seems to lower the risk of stomach cancer.
Possibly ineffective for...
- Colon cancer, rectal cancer. Regularly eating oat bran or oats doesn't seem to lower the risk of colon or rectal cancer.
Is it safe?
When applied to the skin: Lotion containing oat extract is possibly safe to use on the skin. Putting oat-containing products on the skin can cause some people to have a rash.
Special precautions & warnings:
Pregnancy and breast-feeding: Oat bran and whole oats are likely safe when eaten in foods during pregnancy and breast-feeding.Celiac disease: People with celiac disease must not eat gluten. Many people with celiac disease are told to avoid eating oats because they might be contaminated with wheat, rye, or barley, which contain gluten. But in people who haven't had any symptoms for at least 6 months, eating moderate amounts of pure, non-contaminated oats seems to be safe.
Disorders of the digestive tract including the esophagus, stomach, and intestines: Avoid eating oat products. Digestive problems that could extend the length of time it takes for your food to be digested could allow oats to block your intestine.
Are there interactions with medications?
- Insulin
- Oats might reduce the amount of insulin needed for blood sugar control. Taking oats along with insulin might cause your blood sugar to drop too low. Monitor your blood sugar closely. The dose of insulin might need to be changed.
- Medications for diabetes (Antidiabetes drugs)
- Oats might lower blood sugar levels. Taking oats along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
Are there interactions with herbs and supplements?
- Herbs and supplements that might lower blood sugar
- Oats might lower blood sugar. Taking it with other supplements with similar effects might lower blood sugar too much. Examples of supplements with this effect include aloe, bitter melon, cassia cinnamon, chromium, and prickly pear cactus.
Are there interactions with foods?
- There are no known interactions with foods.
How is it typically used?
Other names
Methodology
To learn more about how this article was written, please see the Natural Medicines Comprehensive Database methodology.
References
- Xu D, Pan D, Liu H, et al. Improvement in cardiometabolic risk markers following an oatmeal diet is associated with gut microbiota in mildly hypercholesterolemic individuals. Food Res Int 2022;160:111701. View abstract.
- Xi H, Zhou W, Niu Y, et al. Effect of Oat Consumption on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Acad Nutr Diet 2023;123:809-823. View abstract.
- Pereira-Caro G, Almutairi TM, Cáceres-Jiménez S, et al. Bioavailability of orange juice (poly)phenols: ß-glucan-rich oat bran decreases urinary excretion of flavanone phase II metabolites and enhances excretion of microbiota-derived phenolic catabolites. Free Radic Biol Med 2023;199:34-43. View abstract.
- González-Afonso M, Cañas JA, Sastre B, et al. A Case of Anaphylaxis After Ingestion of Oats: Research Into New Allergens. J Investig Allergol Clin Immunol 2022;32:506-508. View abstract.
- de Morais Junior AC, Schincaglia RM, Viana RB, et al. The separate effects of whole oats and isolated beta-glucan on lipid profile: A systematic review and meta-analysis of randomized controlled trials. Clin Nutr ESPEN 2023;53:224-237. View abstract.
- Kim SJ, Jung CW, Anh NH, et al. Effects of Oats (Avena sativa L.) on Inflammation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Nutr 2021;8:722866. View abstract.
- 107751 Barati Z, Iravani M, Karandish M, Haghighizadeh MH, Masihi S. The effect of oat bran consumption on gestational diabetes: a randomized controlled clinical trial. BMC Endocr Disord 2021;21:67. View abstract.
- Xue Y, Cui L, Qi J, et al. The effect of dietary fiber (oat bran) supplement on blood pressure in patients with essential hypertension: A randomized controlled trial. Nutr Metab Cardiovasc Dis 2021;31:2458-2470. View abstract.
- Xu D, Feng M, Chu Y, et al. The Prebiotic Effects of Oats on Blood Lipids, Gut Microbiota, and Short-Chain Fatty Acids in Mildly Hypercholesterolemic Subjects Compared With Rice: A Randomized, Controlled Trial. Front Immunol 2021;12:787797. View abstract.
- Musa-Veloso K, Noori D, Venditti C, et al. A systematic review and meta-analysis of randomized controlled trials on the effects of oats and oat processing on postprandial blood glucose and insulin responses. J Nutr 2021;151:341-51. View abstract.
- Zeng Z, Jendricke P, Centner C, Storck H, Gollhofer A, König D. Acute effects of oatmeal on exercise-induced reactive oxygen species production following high-intensity interval training in women: a randomized controlled trial. Antioxidants (Basel). 2020 Dec 22;10:3. doi: 10.3390/antiox10010003. View abstract.
- Bozbulut R, Sanlier N, Döger E, Bideci A, Çamurdan O, Cinaz P. The effect of beta-glucan supplementation on glycemic control and variability in adolescents with type 1 diabetes mellitus. Diabetes Res Clin Pract. 2020;169:108464. View abstract.
- Hou Q, Li Y, Li L, Cheng G, Sun X, Li S, Tian H. The metabolic effects of oats intake in patients with type 2 diabetes: A systematic review and meta-analysis. Nutrients. 2015;7:10369-87. View abstract.
- Capone K, Kirchner F, Klein SL, Tierney NK. Effects of colloidal oatmeal topical atopic dermatitis cream on skin microbiome and skin barrier properties. J Drugs Dermatol. 2020;19:524-531. View abstract.
- Andersen JLM, Hansen L, Thomsen BLR, Christiansen LR, Dragsted LO, Olsen A. Pre- and post-diagnostic intake of whole grain and dairy products and breast cancer prognosis: the Danish Diet, Cancer and Health cohort. Breast Cancer Res Treat. 2020;179:743-753. View abstract.
- Leão LSCS, Aquino LA, Dias JF, Koifman RJ. Addition of oat bran reduces HDL-C and does not potentialize effect of a low-calorie diet on remission of metabolic syndrome: A pragmatic, randomized, controlled, open-label nutritional trial. Nutrition. 2019;65:126-130. View abstract.
- Zhang T, Zhao T, Zhang Y, et al. Avenanthramide supplementation reduces eccentric exercise-induced inflammation in young men and women. J Int Soc Sports Nutr. 2020;17:41. View abstract.
- Sobhan M, Hojati M, Vafaie SY, Ahmadimoghaddam D, Mohammadi Y, Mehrpooya M. The efficacy of colloidal oatmeal cream 1% as add-on therapy in the management of chronic irritant hand eczema: A double-blind study. Clin Cosmet Investig Dermatol. 2020;13:241-251. View abstract.
- Alakoski A, Hervonen K, Mansikka E, et al. The long-term safety and quality of life effects of oats in dermatitis herpetiformis. Nutrients. 2020;12:1060. View abstract.
- Spector Cohen I, Day AS, Shaoul R. To be oats or not to be? An update on the ongoing debate on oats for patients with celiac disease. Front Pediatr. 2019;7:384. View abstract.
- Lyskjær L, Overvad K, Tjønneland A, Dahm CC. Substitutions of oatmeal and breakfast food alternatives and the rate of stroke. Stroke. 2020;51:75-81. View abstract.
- Delgado G, Kleber ME, Krämer BK, et al. Dietary intervention with oatmeal in patients with uncontrolled type 2 diabetes mellitus - A crossover study. Exp Clin Endocrinol Diabetes. 2019;127:623-629. View abstract.
- Electronic Code of Federal Regulations. Title 21. Part 101. Subpart E - Specific Requirement for Health Claims. Available at: http://www.ecfr.gov/cgi-bin/text-idx?SID=c7e427855f12554dbc292b4c8a7545a0&mc=true&node=pt21.2.101&rgn=div5#se21.2.101_176. Accessed on March 9, 2020.
- Tiong SH, Looi CY, Hazni H, et al. Antidiabetic and antioxidant properties of alkaloids from Catharanthus roseus (L.) G. Don. Molecules. 2013 Aug 15;18:9770-84. View abstract.
- Pridal AA, Böttger W, Ross AB. Analysis of avenanthramides in oat products and estimation of avenanthramide intake in humans. Food Chem 2018;253:93-100. doi: 10.1016/j.foodchem.2018.01.138. View abstract.
- Kyrø C, Tjønneland A, Overvad K, Olsen A, Landberg R. Higher Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes among Middle-Aged Men and Women: The Danish Diet, Cancer, and Health Cohort. J Nutr 2018;148:1434-44. doi: 10.1093/jn/nxy112. View abstract.
- Mackie AR, Bajka BH, Rigby NM, et al. Oatmeal particle size alters glycemic index but not as a function of gastric emptying rate. Am J Physiol Gastrointest Liver Physiol. 2017;313:G239-G246. View abstract.
- Li X, Cai X, Ma X, et al. Short- and Long-Term Effects of Wholegrain Oat Intake on Weight Management and Glucolipid Metabolism in Overweight Type-2 Diabetics: A Randomized Control Trial. Nutrients. 2016;8. View abstract.
- Kennedy DO, Jackson PA, Forster J, et al. Acute effects of a wild green-oat (Avena sativa) extract on cognitive function in middle-aged adults: A double-blind, placebo-controlled, within-subjects trial. Nutr Neurosci. 2017;20:135-151. View abstract.
- Ilnytska O, Kaur S, Chon S, et al. Colloidal Oatmeal (Avena Sativa) Improves Skin Barrier Through Multi-Therapy Activity. J Drugs Dermatol. 2016;15:684-90. View abstract.
- Reynertson KA, Garay M, Nebus J, Chon S, Kaur S, Mahmood K, Kizoulis M, Southall MD. Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin. J Drugs Dermatol. 2015 Jan;14:43-8. View abstract.
- Nakhaee S, Nasiri A, Waghei Y, Morshedi J. Comparison of Avena sativa, vinegar, and hydroxyzine for uremic pruritus of hemodialysis patients: a crossover randomized clinical trial. Iran J Kidney Dis. 2015 Jul;9:316-22. View abstract.
- Krag A, Munkholm P, Israelsen H, von Ryberg B, Andersen KK, Bendtsen F. Profermin is efficacious in patients with active ulcerative colitis--a randomized controlled trial. Inflamm Bowel Dis. 2013;19:2584-92. View abstract.
- Cooper SG, Tracey EJ. Small-bowel obstruction caused by oat-bran bezoar. N Engl J Med 1989;320:1148-9. View abstract.
- Hendricks KM, Dong KR, Tang AM, et al. High-fiber diet in HIV-positive men is associated with lower risk of developing fat deposition. Am J Clin Nutr 2003;78:790-5. View abstract.
- Storsrud S, Olsson M, Arvidsson Lenner R, et al. Adult coeliac patients do tolerate large amounts of oats. Eur J Clin Nutr 2003;57:163-9. . View abstract.
- De Paz Arranz S, Perez Montero A, Remon LZ, Molero MI. Allergic contact urticaria to oatmeal. Allergy 2002;57:1215. . View abstract.
- Lembo A, Camilleri M. Chronic constipation. N Engl J Med 2003;349:1360-8. . View abstract.
- Rao SS. Constipation: evaluation and treatment. Gastroenterol Clin North Am 2003;32:659-83.. View abstract.
- Jenkins DJ, Wesson V, Wolever TM, et al. Wholemeal versus wholegrain breads: proportion of whole or cracked grain and the glycaemic response. BMJ 1988;297:958-60. View abstract.
- Terry P, Lagergren J, Ye W, et al. Inverse association between intake of cereal fiber and risk of gastric cardia cancer. Gastroenterology 2001;120:387-91.. View abstract.
- Kerckhoffs DA, Hornstra G, Mensink RP. Cholesterol-lowering effect of beta-glucan from oat bran in mildly hypercholesterolemic subjects may decrease when beta-glucan is incorporated into bread and cookies. Am J Clin Nutr 2003;78:221-7.. View abstract.
- Chandalia M, Garg A, Lutjohann D, et al. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med 2000;342:1392-8. View abstract.
- Maier SM, Turner ND, Lupton JR. Serum lipids in hypercholesterolemic men and women consuming oat bran and amaranth products. Cereal Chem 2000:77;297-302.
- Foulke J. FDA Allows Whole Oat Foods To Make Health Claim on Reducing the Risk of Heart Disease. FDA Talk Paper. 1997. Available at: http://www.fda.gov/bbs/topics/ANSWERS/ANS00782.html.
- Braaten JT, Wood PJ, Scott FW, et al. Oat beta-glucan reduces blood cholesterol concentration in hypercholesterolemic subjects. Eur J Clin Nutr 1994;48:465-74. View abstract.
- Anderson JW, Gilinsky NH, Deakins DA, et al. Lipid responses of hypocholesterolemic men to oat-bran and wheat-bran intake. Am J Clin Nutr. 1991;54:678-83. View abstract.
- Van Horn LV, Liu K, Parker D, et al. Serum lipid response to oat product intake with a fat-modified diet. J Am Diet Assoc 1986;86:759-64. View abstract.
- Food and Drug Administration. Food labeling: health claims: oats and coronary heart disease. Fed Regist 1996;61:296-313.
- Lia A, Hallmans G, Sandberg AS, et al. Oat beta-glucan increases bile acid excretion and a fiber-rich barley fraction increases cholesterol excretion in ileostomy subjects. Am J Clin Nutr 1995;62:1245-51. View abstract.
- Brown L, Rosner B, Willett WW, Sacks FM. Cholesterol-lowering effects of dietary fiber: a meta-analysis. Am J Clin Nutr 1999;69:30-42. View abstract.
- Ripsen CM, Keenan JM, Jacobs DR, et al. Oat products and lipid lowering. A meta-analysis. JAMA 1992;267:3317-25. View abstract.
- Davidson MH, Dugan LD, Burns JH, et al. The hypocholesterolemic effects of beta-glucan in oatmeal and oat bran. JAMA 1991;265:1833-9. View abstract.
- Dwyer JT, Goldin B, Gorbach S, Patterson J. Drug therapy reviews: dietary fiber and fiber supplements in the therapy of gastrointestinal disorders. Am J Hosp Pharm 1978;35:278-87. View abstract.
- Kritchevsky D. Dietary fibre and cancer. Eur J Cancer Prev 1997;6:435-41. View abstract.
- Almy TP, Howell DA. Medical progress; Diverticular disease of the colon. N Engl J Med 1980;302:324-31.
- Almy TP. Fiber and the gut. Am J Med 1981;71:193-5.
- Reddy BS. Role of dietary fiber in colon cancer: an overview. Am J Med 1999;106:16S-9S. View abstract.
- Rosario PG, Gerst PH, Prakash K, Albu E. Dentureless distention: oat bran bezoars cause obstruction. J Am Geriatr Soc 1990;38:608.
- Arffmann S, Hojgaard L, Giese B, Krag E. Effect of oat bran on lithogenic index of bile and bile acid metabolism. Digestion 1983;28:197-200. View abstract.
- Braaten JT, Wood PJ, Scott FW, Riedel KD, et al. Oat gum lowers glucose and insulin after an oral glucose load. Am J Clin Nutr 1991;53:1425-30. View abstract.
- Braaten JT, Scott FW, Wood PJ, et al. High beta-glucan oat bran and oat gum reduce postprandial blood glucose and insulin in subjects with and without type 2 diabetes. Diabet Med 1994;11:312-8. View abstract.
- Wood PJ, Braaten JT, Scott FW, et al. Effect of dose and modification of viscous properties of oat gum on plasma glucose and insulin following an oral glucose load. Br J Nutr 1994;72:731-43. View abstract.
- Pick ME, Hawrysh ZJ, Gee MI, et al. Oat bran concentrate bread products improve long-term control of diabetes: a pilot study. J Am Diet Assoc 1996;96:1254-61. View abstract.
- Cooper SG, Tracey EJ. Small-bowel obstruction caused by oat-bran bezoar. N Engl J Med 1989;320:1148-9.
- Ripsin CM, Keenan JM, Jacobs DR Jr, et al. Oat products and lipid lowering. A meta-analysis. JAMA 1992;267:3317-25. View abstract.
- Braaten JT, Wood PJ, Scott FW, et al. Oat beta-glucan reduces blood cholesterol concentration in hypercholesterolemic subjects. Eur J Clin Nutr 1994;48:465-74. View abstract.
- Marlett JA, Hosig KB, Vollendorf NW, et al. Mechanism of serum cholesterol reduction by oat bran. Hepatol 1994;20:1450-7. View abstract.
- Romero AL, Romero JE, Galaviz S, Fernandez ML. Cookies enriched with psyllium or oat bran lower plasma LDL cholesterol in normal and hypercholesterolemic men from Northern Mexico. J Am Coll Nutr 1998;17:601-8. View abstract.
- Chen HL, Haack VS, Janecky CW, et al. Mechanisms by which wheat bran and oat bran increase stool weight in humans. Am J Clin Nutr 1998;68:711-9. View abstract.
- American Dietetic Association Website. Available at: www.eatright.org/adap1097.html (Accessed 16 July 1999).
- Kromhout D, de Lezenne C, Coulander C. Diet, prevalence and 10-year mortality from coronary heart disease in 871 middle-aged men. The Zutphen Study. Am J Epidemiol 1984;119:733-41. View abstract.
- Morris JN, Marr JW, Clayton DG. Diet and heart: a postscript. Br Med J 1977;2:1307-14. View abstract.
- Khaw KT, Barrett-Connor E. Dietary fiber and reduced ischemic heart disease mortality rates in men and women: a 12-year prospective study. Am J Epidemiol 1987;126:1093-102. View abstract.
- He J, Klag MJ, Whelton PK, et al. Oats and buckwheat intakes and cardiovascular disease risk factors in an ethnic minority of China. Am J Clin Nutr 1995;61:366-72. View abstract.
- Rimm EB, Ascherio A, Giovannucci E, et al. Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men. JAMA 1996;275:447-51. View abstract.
- Van Horn L. Fiber, lipids, and coronary heart disease. A statement for healthcare professionals from the Nutr Committee, Am Heart Assn. Circulation 1997;95:2701-4. View abstract.
- Pietinen P, Rimm EB, Korhonen P, et al. Intake of dietary fiber and risk of coronary heart disease in a cohort of Finnish men. The alpha-tocopherol, beta-carotene cancer prevention study. Circulation 1996;94:2720-7. View abstract.
- Wursch P, Pi-Sunyer FX. The role of viscous soluble fiber in the metabolic control of diabetes. A review with special emphasis on cereals rich in beta-glucan. Diabetes Care 1997;20:1774-80. View abstract.
- FDA Talk Paper. FDA Allows Whole Oat Foods to make Claim on Reducing the Risk of Heart Disease. 1997. Available at: vm.cfsan.fda.gov/~lrd/tpoats.html.
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Schatzkin A, Lanza E, Corle D, et al. Lack of effect of a low-fat, high-fiber diet on the recurrence of colorectal adenomas. Polyp Prevention Trial Study Group. N Engl J Med 2000;342:1149-55. View abstract.
- Davy BM, Melby CL, Beske SD, et al. Oat consumption does not affect resting casual and ambulatory 24-h arterial blood pressure in men with high-normal blood pressure to stage I hypertension. J Nutr 2002;132:394-8.. View abstract.
- Ludwig DS, Pereira MA, Kroenke CH, et al. Dietary fiber, weight gain, and cardiovascular disease risk factors in young adults. JAMA 1999;282:1539-46. View abstract.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.