Von Hippel-Lindau disease (VHL) is a rare, genetic disease that causes tumors and cysts to grow in your body. The tumors can be either cancerous or benign. They can grow in your brain and spinal cord, kidneys, pancreas and, in men, their genital tract. Symptoms of VHL vary and depend on the size and location of the tumors. They may include headaches, problems with balance and walking, dizziness, weakness of the limbs, vision problems and high blood pressure.
Detecting and treating VHL early is important. Treatment usually involves surgery or sometimes radiation therapy. The goal is to treat growths while they are small and before they do permanent damage.
NIH: National Institute of Neurological Disorders and Stroke
- Genetics Home Reference: von Hippel-Lindau syndrome (National Library of Medicine)
- ClinicalTrials.gov: von Hippel-Lindau Disease (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Posterior Pole and Peripheral Retinal Fibrovascular Proliferation in von Hippel...
- Article: VHL promotes immune response against renal cell carcinoma via NF-κB-dependent...
- Article: Zebrafish as a model for von Hippel Lindau and hypoxia-inducible...
- Von Hippel-Lindau Disease -- see more articles