Learn More
See, Play and Learn
- No links available
Research
Resources
For You
Summary
Tuberous sclerosis is a rare genetic disease that causes benign tumors to grow in the brain and other organs. Symptoms vary, depending on where the tumors grow. They could include:
- Skin problems, such as light patches and thickened skin
- Seizures
- Behavior problems
- Intellectual disabilities
- Kidney problems
Some people have signs of tuberous sclerosis at birth. In others it can take time for the symptoms to develop. The disease can be mild, or it can cause severe disabilities. In rare cases, tumors in vital organs or other symptoms can be life-threatening.
Tuberous sclerosis has no cure, but treatments can help symptoms. Options include medicines, educational and occupational therapy, surgery, or surgery to treat specific complications.
NIH: National Institute of Neurological Disorders and Stroke
Treatments and Therapies
-
Tuberous Sclerosis: Diagnosis and Treatment
(Mayo Foundation for Medical Education and Research)
Living With
-
Medical Specialists
(TSC Alliance)
- PDF
-
Steps to Reduce SUDEP
(TSC Alliance)
- PDF
Specifics
-
Autosomal Dominant Polycystic Kidney Disease Type 1 with Tuberous Sclerosis
(Genetic and Rare Diseases Information Center)
Genetics
-
Reproductive Decision Making and TSC
(TSC Alliance)
- PDF
-
Tuberous sclerosis complex: MedlinePlus Genetics
(National Library of Medicine)
Clinical Trials
-
ClinicalTrials.gov: Tuberous Sclerosis
(National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Kidney Cyst Epithelia in Tuberous Sclerosis Complex (TSC) Exhibit Propagation and...
- Article: Executive summary of the Japanese clinical practice guidelines for tuberous sclerosis...
- Article: Molecular Characterization of TSC1 and TSC2 Variants in a Greek Cohort...
- Tuberous Sclerosis -- see more articles
Find an Expert
Children
-
Infantile or Epileptic Spasms and Tuberous Sclerosis Complex
(TSC Alliance)
- PDF
- Tuberous Sclerosis Complex (For Parents) (Nemours Foundation) Also in Spanish
Patient Handouts
- Tuberous sclerosis (Medical Encyclopedia) Also in Spanish