Tuberous sclerosis is a rare genetic disease that causes benign tumors to grow in the brain and other organs. Symptoms vary, depending on where the tumors grow. They could include:
- Skin problems, such as light patches and thickened skin
- Behavior problems
- Intellectual disabilities
- Kidney problems
Some people have signs of tuberous sclerosis at birth. In others it can take time for the symptoms to develop. The disease can be mild, or it can cause severe disabilities. In rare cases, tumors in vital organs or other symptoms can be life-threatening.
Tuberous sclerosis has no cure, but treatments can help symptoms. Options include medicines, educational and occupational therapy, surgery, or surgery to treat specific complications.
NIH: National Institute of Neurological Disorders and Stroke
- Tuberous Sclerosis Complex (National Institute of Neurological Disorders and Stroke)
- Attention Deficit Hyperactivity Disorder and Tuberous Sclerosis Complex (TSC Alliance) - PDF
- Cognitive Challenges (TSC Alliance) - PDF
- Epilepsy in Adults with TSC (TSC Alliance)
- Tuberous sclerosis complex: MedlinePlus Genetics (National Library of Medicine)
- ClinicalTrials.gov: Tuberous Sclerosis (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Refractive Errors, Retinal Findings, and Genotype of Tuberous Sclerosis Complex: A...
- Article: Profiles of autism characteristics in thirteen genetic syndromes: a machine learning...
- Article: Clinical features and outcomes of male patients with lymphangioleiomyomatosis: A review.
- Tuberous Sclerosis -- see more articles