Fucus Vesiculosus

Existe interés en usar Fucus vesiculosus para varios propósitos, pero no hay suficiente información confiable para decir si podría ser útil.

Advertencias y precauciones especiales:

Moderadas

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Amiodarona (Cordarone)

Tanto el fucus vesiculosus como la amiodarona contienen yodo. Tomar fucus vesiculosus con amiodarona podría aumentar los niveles de yodo en la sangre. Demasiado yodo en la sangre puede causar efectos secundarios que afectan la tiroides.

Hormona tiroidea

Fucus vesiculosus contiene yodo. El yodo puede aumentar o disminuir la función tiroidea. Tomar Fucus vesiculosus junto con medicamentos de hormona tiroidea podría aumentar los efectos de estos medicamentos.

Litio

Fucus vesiculosus puede contener grandes cantidades de yodo. Grandes cantidades de yodo pueden alterar la función tiroidea. El litio también puede cambiar la función tiroidea. La ingesta de Fucus vesiculosus junto con litio podría aumentar el riesgo de cambios en la función tiroidea.

Medicamentos para una tiroides hiperactiva (medicamentos antitiroideos)

Fucus vesiculosus puede contener grandes cantidades de yodo. El yodo puede aumentar o disminuir la función tiroidea. La ingesta de Fucus vesiculosus junto con medicamentos para la tiroides hiperactiva podría cambiar los efectos de estos medicamentos.

Medicamentos que retardan la coagulación de la sangre (medicamentos anticoagulantes / antiplaquetarios)

El fucus vesiculosus podría retrasar la coagulación sanguínea. La ingesta de Fucus vesiculosus junto con medicamentos que también retrasa la coagulación de la sangre puede aumentar el riesgo de hematomas y hemorragias.

Menores

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Medicamentos modificados por el hígado (sustratos del citocromo P450 2C8 (CYP2C8))

Algunos medicamentos son modificados y degradados por el hígado. El fucus vesiculosus podría cambiar la rapidez con que el hígado descompone estos medicamentos. Esto podría cambiar los efectos y los efectos secundarios de estos medicamentos.

Medicamentos modificados por el hígado (sustratos del citocromo P450 2C9 (CYP2C9))

Algunos medicamentos son modificados y degradados por el hígado. El fucus vesiculosus podría cambiar la rapidez con que el hígado descompone estos medicamentos. Esto podría cambiar los efectos y los efectos secundarios de estos medicamentos.

Medicamentos modificados por el hígado (sustratos del citocromo P450 2D6 (CYP2D6))

Algunos medicamentos son modificados y degradados por el hígado. El fucus vesiculosus podría cambiar la rapidez con que el hígado descompone estos medicamentos. Esto podría cambiar los efectos y los efectos secundarios de estos medicamentos.

Medicamentos modificados por el hígado (sustratos del citocromo P450 3A4 (CYP3A4))

Algunos medicamentos son modificados y degradados por el hígado. El fucus vesiculosus podría cambiar la rapidez con que el hígado descompone estos medicamentos. Esto podría cambiar los efectos y los efectos secundarios de estos medicamentos.

Estronio

Fucus vesiculosus contiene alginato. El alginato puede reducir la absorción de estroncio. La ingesta de Fucus vesiculosus con suplementos de estroncio podría reducir la absorción de estroncio.

Hierbas y suplementos que contienen yodo

Fucus vesiculosus contiene yodo. Tomar Fucus vesiculosus con otros productos que contienen yodo puede causar que los niveles de yodo suban demasiado. Esto puede causar efectos secundarios, como cambios en la función tiroidea. Los ejemplos de suplementos que contienen yodo incluyen productos de algas, como dulse y laminaria.

Hierbas y suplementos que pueden retardar la coagulación sanguínea

El fucus vesiculosus podría retardar la coagulación sanguínea y aumentar el riesgo de hemorragia. Tomarlo con otros suplementos con efectos similares podría aumentar el riesgo de hemorragia en algunas personas. Ejemplos de suplementos con este efecto incluyen ajo, jengibre, ginkgo, nattokinasa y Panax ginseng.

No se conoce ninguna interacción con alimentos.

Para saber más sobre cómo este artículo fue escrito, refiérase a la metodología de la Base exhaustiva de datos de medicamentos naturales.

1. Vodouhè M, Marois J, Guay V, et al. Marginal impact of brown seaweed Ascophyllum nodosum and Fucus vesiculosus extract on metabolic and inflammatory response in overweight and obese prediabetic subjects. Mar Drugs 2022;20:174. View abstract.
2. Nicolucci A, Rossi MC, Petrelli M. Effectiveness of Ascophyllum nodosum and Fucus vesiculosus on metabolic syndrome components: a real-world, observational study. J Diabetes Res 2021;2021:3389316. View abstract.
3. Murray M, Dordevic AL, Cox K, Scholey A, Ryan L, Bonham MP. Twelve weeks' treatment with a polyphenol-rich seaweed extract increased HDL cholesterol with no change in other biomarkers of chronic disease risk in overweight adults: A placebo-controlled randomized trial. J Nutr Biochem 2021;96:108777. View abstract.
4. Heavisides E, Rouger C, Reichel AF, et al. Seasonal Variations in the Metabolome and Bioactivity Profile of Fucus vesiculosus Extracted by an Optimised, Pressurised Liquid Extraction Protocol. Mar Drugs. 2018;16. pii: E503. View abstract.
5. Derosa G, Cicero AFG, D'Angelo A, Maffioli P. Ascophyllum nodosum and Fucus vesiculosus on glycemic status and on endothelial damage markers in dysglicemic patients. Phytother Res. 2019;33:791-797. View abstract.
6. Mathew L, Burney M, Gaikwad A, et al. Preclinical evaluation of safety of fucoidan extracts from Undaria pinnatifida and Fucus vesiculosus for use in cancer treatment. Integr Cancer Ther 2017;16:572-84. View abstract.
7. Wikström SA, Kautsky L. Structure and diversity of invertebrate communities in the presence and absence of canopy-forming Fucus vesiculosus in the Baltic Sea. Estuarine Coastal Shelf Sci 2007;72:168-176.
8. Torn K, Krause-Jensen D, Martin G. Present and past depth distribution of bladderwrack (Fucus vesiculosus) in the Baltic Sea. Aquatic Botany 2006;84:53-62.
9. Hoang TD, Mai VQ, Clyde PW, Shakir MK. Over-the-counter-drug-induced thyroid disorders. Endocr Pract. 2013 Mar-Apr;19:268-74. View abstract.
10. Alraei, RG. Herbal and Dietary Supplements for Weight Loss. Topics in Clinical Nutrition. 2010;25:136-150.
11. Bradley MD, Nelson A Petticrew M Cullum N Sheldon T. Dressing for pressure sores. Cochrane Library 2011;0:0.
12. Schreuder SM, Vermeulen H Qureshi MA Ubbink DT. Dressings and topical agents for donor sites of split-thickness skin grafts. JOURNAL 2009;0:0.
13. Martyn-St James M., O'Meara S. Foam dressings for venous leg ulcers. Cochrane Library. 2012;0:0.
14. Ewart, S Girouard G. Tiller C. et al. Antidiabetic Activities of a Seaweed Extract. Diabetes. 2004;53(Supplement 2):A509.
15. Lindsey, H. Use of Botanicals for Cancer: Systematic Research Required to Determine Role. Oncology Times. 2005;27:52-55.
16. Le Tutour B, Benslimane F, Gouleau MP, and et al. Antioxidant and pro-oxidant activities of the brown algae, Laminaria digitata, Himanthalia elongata, Fucus vesiculosus, Fucus serratus and Ascophyllum nodosum. J Applied Phycology 1998;10:121-129.
17. Eliason, B. C. Transient hyperthyroidism in a patient taking dietary supplements containing kelp. J Am Board Fam.Pract. 1998;11:478-480. View abstract.
18. Gaigi, S., Elati, J., Ben, Osman A., and Beji, C. [Experimental study of the effects of seaweed in the treatment of obesity]. Tunis Med. 1996;74:241-243. View abstract.
19. Drozhzhina, V. A., Fedorov, IuA, Blokhin, V. P., Soboleva, T. I., and Kazakova, O. V. [The use of dental elixirs based on natural biologically active substances in the treatment and prevention of periodontal diseases]. Stomatologiia (Mosk) 1996;Spec No:52-53. View abstract.
20. Yamamoto I, Nagumo T, Fujihara M, and et al. Antitumor effect of seaweeds. II. Fractionation and partial characterization of the polysaccharide with antitumor activity from Sargassum fulvellum. Jpn.J Exp Med 1977;47:133-140. View abstract.
21. Monego, E. T., Peixoto, Mdo R., Jardim, P. C., Sousa, A. L., Braga, V. L., and Moura, M. F. [Different therapies in the treatment of obesity in hypertensive patients]. Arq Bras.Cardiol. 1996;66:343-347. View abstract.
22. Riou D, Colliec-Jouault S, Pinczon du Sel D, and et al. Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line. Anticancer Res 1996;16(3A):1213-1218. View abstract.
23. Sakata, T. A very-low-calorie conventional Japanese diet: its implications for prevention of obesity. Obes.Res. 1995;3 Suppl 2:233s-239s. View abstract.
24. Ellouali M, Boisson-Vidal C, Durand P, and et al. Antitumor activity of low molecular weight fucans extracted from brown seaweed Ascophyllum nodosum. Anticancer Res 1993;13(6A):2011-2020. View abstract.
25. Drnek, F., Prokes, B., and Rydlo, O. [Experiment in affecting cancer biologically with an intramuscular and local administration of the seaweed, Scenedesmus obliquus]. Cesk.Gynekol. 1981;46:463-465. View abstract.
26. Criado, M. T. and Ferreiros, C. M. Selective interaction of a Fucus vesiculosus lectin-like mucopolysaccharide with several Candida species. Ann Microbiol (Paris) 1983;134A:149-154. View abstract.
27. Shilo, S. and Hirsch, H. J. Iodine-induced hyperthyroidism in a patient with a normal thyroid gland. Postgrad Med J 1986;62:661-662. View abstract.
28. Church FC, Meade JB, Treanor RE, and et al. Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin. J Biol Chem 2-25-1989;264:3618-3623. View abstract.
29. Grauffel V, Kloareg B, Mabeau S, and et al. New natural polysaccharides with potent antithrombic activity: fucans from brown algae. Biomaterials 1989;10:363-368. View abstract.
30. Lamela M, Anca J, Villar R, and et al. Hypoglycemic activity of several seaweed extracts. J.Ethnopharmacol. 1989;27(1-2):35-43. View abstract.
31. Maruyama H, Nakajima J, and Yamamoto I. A study on the anticoagulant and fibrinolytic activities of a crude fucoidan from the edible brown seaweed Laminaria religiosa, with special reference to its inhibitory effect on the growth of sarcoma-180 ascites cells subcutaneously implanted into mice. Kitasato Arch Exp Med 1987;60:105-121. View abstract.
32. Obiero, J., Mwethera, P. G., and Wiysonge, C. S. Topical microbicides for prevention of sexually transmitted infections. Cochrane.Database.Syst.Rev. 2012;6:CD007961. View abstract.
33. Park, K. Y., Jang, W. S., Yang, G. W., Rho, Y. H., Kim, B. J., Mun, S. K., Kim, C. W., and Kim, M. N. A pilot study of silver-loaded cellulose fabric with incorporated seaweed for the treatment of atopic dermatitis. Clin.Exp.Dermatol. 2012;37:512-515. View abstract.
34. Michikawa, T., Inoue, M., Shimazu, T., Sawada, N., Iwasaki, M., Sasazuki, S., Yamaji, T., and Tsugane, S. Seaweed consumption and the risk of thyroid cancer in women: the Japan Public Health Center-based Prospective Study. Eur.J.Cancer Prev. 2012;21:254-260. View abstract.
35. Capitanio, B., Sinagra, J. L., Weller, R. B., Brown, C., and Berardesca, E. Randomized controlled study of a cosmetic treatment for mild acne. Clin.Exp.Dermatol. 2012;37:346-349. View abstract.
36. Marais, D., Gawarecki, D., Allan, B., Ahmed, K., Altini, L., Cassim, N., Gopolang, F., Hoffman, M., Ramjee, G., and Williamson, A. L. The effectiveness of Carraguard, a vaginal microbicide, in protecting women against high-risk human papillomavirus infection. Antivir.Ther. 2011;16:1219-1226. View abstract.
37. Cho, H. B., Lee, H. H., Lee, O. H., Choi, H. S., Choi, J. S., and Lee, B. Y. Clinical and microbial evaluation of the effects on gingivitis of a mouth rinse containing an Enteromorpha linza extract. J.Med.Food 2011;14:1670-1676. View abstract.
38. Kang, Y. M., Lee, B. J., Kim, J. I., Nam, B. H., Cha, J. Y., Kim, Y. M., Ahn, C. B., Choi, J. S., Choi, I. S., and Je, J. Y. Antioxidant effects of fermented sea tangle (Laminaria japonica) by Lactobacillus brevis BJ20 in individuals with high level of gamma-GT: A randomized, double-blind, and placebo-controlled clinical study. Food Chem.Toxicol. 2012;50(3-4):1166-1169. View abstract.
39. Arbaizar, B. and Llorca, J. [Fucus vesiculosus induced hyperthyroidism in a patient undergoing concomitant treatment with lithium]. Actas Esp.Psiquiatr. 2011;39:401-403. View abstract.
40. Hall, A. C., Fairclough, A. C., Mahadevan, K., and Paxman, J. R. Ascophyllum nodosum enriched bread reduces subsequent energy intake with no effect on post-prandial glucose and cholesterol in healthy, overweight males. A pilot study. Appetite 2012;58:379-386. View abstract.
41. Paradis, M. E., Couture, P., and Lamarche, B. A randomised crossover placebo-controlled trial investigating the effect of brown seaweed (Ascophyllum nodosum and Fucus vesiculosus) on postchallenge plasma glucose and insulin levels in men and women. Appl.Physiol Nutr.Metab 2011;36:913-919. View abstract.
42. Misurcova, L., Machu, L., and Orsavova, J. Seaweed minerals as nutraceuticals. Adv.Food Nutr.Res. 2011;64:371-390. View abstract.
43. Jeukendrup, A. E. and Randell, R. Fat burners: nutrition supplements that increase fat metabolism. Obes.Rev. 2011;12:841-851. View abstract.
44. Shin, H. C., Kim, S. H., Park, Y., Lee, B. H., and Hwang, H. J. Effects of 12-week oral supplementation of Ecklonia cava polyphenols on anthropometric and blood lipid parameters in overweight Korean individuals: a double-blind randomized clinical trial. Phytother.Res. 2012;26:363-368. View abstract.
45. Pangestuti, R. and Kim, S. K. Neuroprotective effects of marine algae. Mar.Drugs 2011;9:803-818. View abstract.
46. Miyashita, K., Nishikawa, S., Beppu, F., Tsukui, T., Abe, M., and Hosokawa, M. The allenic carotenoid fucoxanthin, a novel marine nutraceutical from brown seaweeds. J.Sci.Food Agric. 2011;91:1166-1174. View abstract.
47. Araya, N., Takahashi, K., Sato, T., Nakamura, T., Sawa, C., Hasegawa, D., Ando, H., Aratani, S., Yagishita, N., Fujii, R., Oka, H., Nishioka, K., Nakajima, T., Mori, N., and Yamano, Y. Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type-1-associated neurological disease. Antivir.Ther. 2011;16:89-98. View abstract.
48. Oh, J. K., Shin, Y. O., Yoon, J. H., Kim, S. H., Shin, H. C., and Hwang, H. J. Effect of supplementation with Ecklonia cava polyphenol on endurance performance of college students. Int.J.Sport Nutr.Exerc.Metab 2010;20:72-79. View abstract.
49. Odunsi, S. T., Vazquez-Roque, M. I., Camilleri, M., Papathanasopoulos, A., Clark, M. M., Wodrich, L., Lempke, M., McKinzie, S., Ryks, M., Burton, D., and Zinsmeister, A. R. Effect of alginate on satiation, appetite, gastric function, and selected gut satiety hormones in overweight and obesity. Obesity.(Silver.Spring) 2010;18:1579-1584. View abstract.
50. Teas, J., Baldeon, M. E., Chiriboga, D. E., Davis, J. R., Sarries, A. J., and Braverman, L. E. Could dietary seaweed reverse the metabolic syndrome? Asia Pac.J.Clin.Nutr. 2009;18:145-154. View abstract.
51. Irhimeh, M. R., Fitton, J. H., and Lowenthal, R. M. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood Coagul.Fibrinolysis 2009;20:607-610. View abstract.
52. Fluhr, J. W., Breternitz, M., Kowatzki, D., Bauer, A., Bossert, J., Elsner, P., and Hipler, U. C. Silver-loaded seaweed-based cellulosic fiber improves epidermal skin physiology in atopic dermatitis: safety assessment, mode of action and controlled, randomized single-blinded exploratory in vivo study. Exp.Dermatol. 2010;19:e9-15. View abstract.
53. Vasilevskaia, L. S., Pogozheva, A. V., Derbeneva, S. A., Zorin, S. N., Buchanova, A. V., Abramova, L. S., Petrukhanova, A. V., Gmoshinskii, I. V., and Mazo, V. K. [Clinical efficiency of using laminaria jam enriched with selenium]. Vopr.Pitan. 2009;78:79-83. View abstract.
54. Frestedt, J. L., Kuskowski, M. A., and Zenk, J. L. A natural seaweed derived mineral supplement (Aquamin F) for knee osteoarthritis: a randomised, placebo controlled pilot study. Nutr.J. 2009;8:7. View abstract.
55. Wasiak, J., Cleland, H., and Campbell, F. Dressings for superficial and partial thickness burns. Cochrane.Database.Syst.Rev. 2008;:CD002106. View abstract.
56. Fowler, E. and Papen, J. C. Evaluation of an alginate dressing for pressure ulcers. Decubitus. 1991;4:47-8, 50, 52. View abstract.
57. Paxman, J. R., Richardson, J. C., Dettmar, P. W., and Corfe, B. M. Daily ingestion of alginate reduces energy intake in free-living subjects. Appetite 2008;51:713-719. View abstract.
58. Frestedt, J. L., Walsh, M., Kuskowski, M. A., and Zenk, J. L. A natural mineral supplement provides relief from knee osteoarthritis symptoms: a randomized controlled pilot trial. Nutr J 2008;7:9. View abstract.
59. Colliec S, Fischer AM, Tapon-Bretaudiere J, and et al. Anticoagulant properties of a fucoidan fraction. Thromb Res 10-15-1991;64:143-154. View abstract.
60. Rowe, B. R., Bain, S. C., Pizzey, M., and Barnett, A. H. Rapid healing of ulcerated necrobiosis lipoidica with optimum glycaemic control and seaweed-based dressings. Br.J.Dermatol. 1991;125:603-604. View abstract.
61. Teas, J., Braverman, L. E., Kurzer, M. S., Pino, S., Hurley, T. G., and Hebert, J. R. Seaweed and soy: companion foods in Asian cuisine and their effects on thyroid function in American women. J Med Food 2007;10:90-100. View abstract.
62. Cumashi, A., Ushakova, N. A., Preobrazhenskaya, M. E., D'Incecco, A., Piccoli, A., Totani, L., Tinari, N., Morozevich, G. E., Berman, A. E., Bilan, M. I., Usov, A. I., Ustyuzhanina, N. E., Grachev, A. A., Sanderson, C. J., Kelly, M., Rabinovich, G. A., Iacobelli, S., and Nifantiev, N. E. A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds. Glycobiology 2007;17:541-552. View abstract.
63. Nelson, E. A. and Bradley, M. D. Dressings and topical agents for arterial leg ulcers. Cochrane.Database.Syst.Rev. 2007;:CD001836. View abstract.
64. Palfreyman, S. J., Nelson, E. A., Lochiel, R., and Michaels, J. A. Dressings for healing venous leg ulcers. Cochrane.Database.Syst.Rev. 2006;:CD001103. [RETRACTED]. View abstract.
65. Maeda, H., Hosokawa, M., Sashima, T., Takahashi, N., Kawada, T., and Miyashita, K. Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. Int.J.Mol.Med. 2006;18:147-152. View abstract.
66. Rudichenko, E. V., Gvozdenko, T. A., and Antoniuk, M. V. [Impact of dietotherapy with enterosorbent of marine origin on the indices of mineral and lipid metabolism for patients suffering from kidney diseases]. Vopr.Pitan. 2005;74:33-35. View abstract.
67. Soeda S, Sakaguchi S, Shimeno H, and et al. Fibrinolytic and anticoagulant activities of highly sulfated fucoidan. Biochem Pharmacol 4-15-1992;43:1853-1858. View abstract.
68. Vermeulen, H., Ubbink, D., Goossens, A., de, Vos R., and Legemate, D. Dressings and topical agents for surgical wounds healing by secondary intention. Cochrane.Database.Syst.Rev. 2004;:CD003554. View abstract.
69. SPRINGER, G. F., WURZEL, H. A., and Mcneal, G. M. et al. Isolation of anticoagulant fractions from crude fucoidin. Proc.Soc.Exp.Biol.Med 1957;94:404-409. View abstract.
70. Bell, J., Duhon, S., and Doctor, V. M. The effect of fucoidan, heparin and cyanogen bromide-fibrinogen on the activation of human glutamic-plasminogen by tissue plasminogen activator. Blood Coagul.Fibrinolysis 2003;14:229-234. View abstract.
71. Cooper, R., Dragar, C., Elliot, K., Fitton, J. H., Godwin, J., and Thompson, K. GFS, a preparation of Tasmanian Undaria pinnatifida is associated with healing and inhibition of reactivation of Herpes. BMC.Complement Altern.Med. 11-20-2002;2:11. View abstract.
72. Abidov, M., Ramazanov, Z., Seifulla, R., and Grachev, S. The effects of Xanthigen in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat. Diabetes Obes.Metab 2010;12:72-81. View abstract.
73. Lis-Balchin, M. Parallel placebo-controlled clinical study of a mixture of herbs sold as a remedy for cellulite. Phytother.Res. 1999;13:627-629. View abstract.
74. Catania, M. A., Oteri, A., Caiello, P., Russo, A., Salvo, F., Giustini, E. S., Caputi, A. P., and Polimeni, G. Hemorrhagic cystitis induced by an herbal mixture. South.Med.J. 2010;103:90-92. View abstract.
75. Bezpalov, V. G., Barash, N. I., Ivanova, O. A., Semenov, I. I., Aleksandrov, V. A., and Semiglazov, V. F. [Investigation of the drug "Mamoclam" for the treatment of patients with fibroadenomatosis of the breast]. Vopr.Onkol. 2005;51:236-241. View abstract.
76. Dumelod, B. D., Ramirez, R. P., Tiangson, C. L., Barrios, E. B., and Panlasigui, L. N. Carbohydrate availability of arroz caldo with lambda-carrageenan. Int.J.Food Sci.Nutr. 1999;50:283-289. View abstract.
77. Burack, J. H., Cohen, M. R., Hahn, J. A., and Abrams, D. I. Pilot randomized controlled trial of Chinese herbal treatment for HIV- associated symptoms. J Acquir.Immune.Defic.Syndr.Hum.Retrovirol. 8-1-1996;12:386-393. View abstract.
78. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. View abstract.
79. US Department of Health and Human Services, Public Health Service. Agency for Toxic Substances and Disease Registry. Toxicological profile for strontium. April 2004. Available at: www.atsdr.cdc.gov/toxprofiles/tp159.pdf. (Accessed 8 August 2006).
80. Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. View abstract.
81. Okamura K, Inoue K, Omae T. A case of Hashimoto's thyroiditis with thyroid immunological abnormality manifested after habitual ingestion of seaweed. Acta Endocrinol (Copenh) 1978;88:703-12. View abstract.
82. Bjorvell H, Rössner S. Long-term effects of commonly available weight reducing programmes in Sweden. Int J Obes 1987;11:67-71. . View abstract.
83. Ohye H, Fukata S, Kanoh M, et al. Thyrotoxicosis caused by weight-reducing herbal medicines. Arch Intern Med 2005;165:831-4. View abstract.
84. Conz PA, La Greca G, Benedetti P, et al. Fucus vesiculosus: a nephrotoxic alga? Nephrol Dial Transplant 1998;13:526-7. View abstract.
85. Fujimura T, Tsukahara K, Moriwaki S, et al. Treatment of human skin with an extract of Fucus vesiculosus changes its thickness and mechanical properties. J Cosmet Sci 2002;53:1-9. View abstract.
86. Koyanagi S, Tanigawa N, Nakagawa H, et al. Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities. Biochem Pharmacol 2003;65:173-9. View abstract.
87. Durig J, Bruhn T, Zurborn KH, et al. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb Res 1997;85:479-91. View abstract.
88. O'Leary R, Rerek M, Wood EJ. Fucoidan modulates the effect of transforming growth factor (TGF)-beta1 on fibroblast proliferation and wound repopulation in in vitro models of dermal wound repair. Biol Pharm Bull 2004;27:266-70. View abstract.
89. Patankar MS, Oehninger S, Barnett T, et al. A revised structure for fucoidan may explain some of its biological activities. J Biol Chem 1993;268:21770-6. View abstract.
90. Baba M, Snoeck R, Pauwels R, de Clercq E. Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus. Antimicrob Agents Chemother 1988;32:1742-5. View abstract.
91. Beress A, Wassermann O, Tahhan S, et al. A new procedure for the isolation of anti-HIV compounds (polysaccharides and polyphenols) from the marine alga Fucus vesiculosus. J Nat Prod 1993;56:478-88. View abstract.
92. Criado MT, Ferreiros CM. Toxicity of an algal mucopolysaccharide for Escherichia coli and Neisseria meningitidis strains. Rev Esp Fisiol 1984;40:227-30. View abstract.
93. Skibola CF. The effect of Fucus vesiculosus, an edible brown seaweed, upon menstrual cycle length and hormonal status in three pre-menopausal women: a case report. BMC Complement Altern Med 2004;4:10. View abstract.
94. Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. View abstract.
95. Baker DH. Iodine toxicity and its amelioration. Exp Biol Med (Maywood) 2004;229:473-8. View abstract.
96. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002. Available at: www.nap.edu/books/0309072794/html/.
97. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
98. Pye KG, Kelsey SM, House IM, et al. Severe dyserythropoeisis and autoimmune thrombocytopenia associated with ingestion of kelp supplement. Lancet 1992;339:1540. View abstract.
99. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.