A lung transplant removes a person's diseased lung and replaces it with a healthy one. The healthy lung comes from a donor who has died. Some people get one lung during a transplant. Other people get two.
Lung transplants are used for people who are likely to die from lung disease within 1 to 2 years. Their conditions are so severe that other treatments, such as medicines or breathing devices, no longer work. Lung transplants most often are used to treat people who have severe
- Cystic fibrosis
- Idiopathic pulmonary fibrosis
- Alpha-1 antitrypsin deficiency
- Pulmonary hypertension
Complications of lung transplantation include rejection of the transplanted lung and infection.
NIH: National Heart, Lung, and Blood Institute
Prevention and Risk Factors
- Preventing Rejection (United Network for Organ Sharing)
- Diet and Exercise (United Network for Organ Sharing)
Statistics and Research
- The SRTR/OPTN Annual Data Report (Scientific Registry of Transplant Recipients)
- ClinicalTrials.gov: Lung Transplantation (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: A Single-Center Experience with Lung Transplants During the COVID-19 Pandemic.
- Article: Considerations for assessing physical function and physical activity in clinical trials...
- Article: A prevalent and culturable microbiota links ecological balance to clinical stability...
- Lung Transplantation -- see more articles
- How the Lungs Work (National Heart, Lung, and Blood Institute)