Summary
Hantavirus pulmonary syndrome (HPS) is a rare viral infection caused by several strains of the hantavirus. It is spread by mice and rats. They shed the virus in their urine, droppings, and saliva. Tiny droplets with the virus can enter the air. You can get the disease if you breathe infected air or come into contact with rodents or their urine or droppings.
Most of the time, you can't get the virus from another person. But one strain of the virus found in South America, called the Andes virus, spreads through close contact with someone who has the virus.
Early symptoms of HPS include:
- Fatigue
- Fever
- Muscle aches, especially in the thighs, hips, and back
- Headaches
- Chills
- Dizziness
- Nausea, vomiting, diarrhea or abdominal (belly) pain
Later symptoms include coughing and shortness of breath.
Controlling rodents in and around your house is the best way to prevent infection. If you have been around rodents and have symptoms of fever, deep muscle aches, and severe shortness of breath, see your health care provider immediately. Early treatment is important.
There is no specific treatment, cure, or vaccine for HPS.
Centers for Disease Control and Prevention
Learn More
- About Hantavirus (Centers for Disease Control and Prevention) Also in Spanish
- Clinical Overview of Hantavirus (Centers for Disease Control and Prevention)
- Clinician Brief: Hemorrhagic Fever with Renal Syndrome (Centers for Disease Control and Prevention)
- Hantavirus Infection (Merck & Co., Inc.) Also in Spanish
- Hantavirus Prevention (Centers for Disease Control and Prevention) Also in Spanish
- Hantavirus Pulmonary Syndrome (Mayo Foundation for Medical Education and Research) Also in Spanish
Clinical Trials
-
ClinicalTrials.gov: Hantavirus Infections
(National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Rapid response and surveillance for high-risk contacts during May 2026 Andes...
- Article: Public health risk assessment of rodent-driven hantavirus spillover in Europe using...
- Article: Andes Hantavirus at FIFA World Cup 2026: No vaccine, no protocol,...
- Hantavirus Infections -- see more articles
Patient Handouts
- Hantavirus (Medical Encyclopedia) Also in Spanish