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While the patient is awake, sleepy (sedated), or deep asleep and pain-free (local anesthesia or general anesthesia), healthy skin is taken from the selected donor site on the patient's body using a dermatome (skin-cutting instrument).
Review Date 4/9/2026
Updated by: Elika Hoss, MD, Assistant Professor of Dermatology, Mayo Clinic, Scottsdale, AZ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.