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Celiac disease

Celiac disease

Overview

The intestinal lining has small hair-like projections called villi, which help absorb nutrients. When people with celiac disease eat foods with gluten, it triggers an immune response. Over time, the inflammation caused by the immune response damages the villi. Because of the damage, the villi are unable to properly absorb iron, vitamins, and other nutrients. This may cause a number of symptoms, including diarrhea, fatigue, and weight loss, as well as a number of other health problems.

Review Date 3/31/2024

Updated by: Jenifer K. Lehrer, MD, Department of Gastroenterology, Aria - Jefferson Health Torresdale, Jefferson Digestive Diseases Network, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.