An intravitreal injection is a shot of medicine into the eye. The inside of the eye is filled with a jelly-like fluid (vitreous). During this procedure, your health care provider injects medicine into the vitreous, near the retina at the back of the eye. The medicine can treat certain eye problems and help protect your vision. This method is most often used to get a higher level of medicine to the retina.
The procedure is done in your provider's office. It takes about 15 to 30 minutes.
- Drops will be placed in your eyes to widen (dilate) the pupils.
- You will lie face up in a comfortable position.
- Your eyes and eyelids will be cleaned.
- Numbing drops will be placed in your eye.
- A small device will keep your eyelids open during the procedure.
- You will be asked to look toward the other eye.
- Medicine will be injected into your eye with a small needle. You may feel pressure, but not pain.
- Antibiotic drops may be placed in your eye.
Why the Procedure is Performed
You may have this procedure if you have:
- Macular degeneration: An eye disorder that slowly destroys sharp, central vision
- Macular edema: Swelling or thickening of the macula, the part of your eye that provides sharp, central vision
- Diabetic retinopathy: A complication of diabetes which can cause new, abnormal blood vessels to grow in the retina, the back part of your eye
- Uveitis: Swelling and inflammation within the eyeball
- Retinal vein occlusion: A blockage of the veins that carry blood away from the retina and out of the eye
- Endophthalmitis: Infection in the inside of the eye
Sometimes, an intravitreal injection of antibiotics and steroids is given as part of routine cataract surgery. This avoids having to use drops after surgery.
Side effects are rare, and many can be managed. They may include:
- Increased pressure in the eye
- Damage to the retina or surrounding nerves or structures
- Vision loss
- Loss of the eye (very rare)
- Side effects from the medicines that are used
Discuss the risks of specific medicines used in your eye with your provider.
Before the Procedure
Tell your provider about:
- Any health problems
- Medicines you take, including any over-the-counter medicines
- Any allergies
- Any bleeding tendencies
After the Procedure
Following the procedure:
- You may feel a few sensations in the eye such as pressure and grittiness, but there should not be pain.
- There may be a little bleeding on the white of the eye. This is normal and will go away.
- You may see eye floaters in your vision. They will improve over time.
- DO NOT rub your eyes for several days.
- Avoid swimming for at least 3 days.
- Use eye drop medicine as directed.
Report any eye pain or discomfort, redness, sensitivity to light, or changes in your vision to your provider right away.
Schedule a follow-up appointment with your provider as directed.
Your outlook depends mostly on the condition being treated. Your vision may remain stable or improve after the procedure. You may need more than one injection.
Antibiotic - intravitreal injection; Triamcinolone - intravitreal injection; Dexamethasone - intravitreal injection; Lucentis - intravitreal injection; Avastin - intravitreal injection; Bevacizumab - intravitreal injection; Ranibizumab - intravitreal injection; Anti-VEGF medicines - intravitreal injection; Macular edema - intravitreal injection; Retinopathy - intravitreal injection; Retinal vein occlusion - intravitreal injection
American Academy of Ophthalmology website. Age-related macular degeneration PPP - updated 2015. www.aao.org/preferred-practice-pattern/age-related-macular-degeneration-ppp-2015. Updated January 2015. Accessed January 19, 2017.
Kent C. Antibiotics & cataract surgery: new frontiers. Review of Ophthalmology. www.reviewofophthalmology.com/article/antibiotics--cataract-surgery-new-frontiers. Updated April 15, 2015. Accessed January 19, 2017.
Mitchell P, Wong TY; Diabetic Macular Edema Treatment Guideline Working Group. Management paradigms for diabetic macular edema. Am J Ophthalmol. 2014;157(3):505-513. PMID: 24269850 www.ncbi.nlm.nih.gov/pubmed/24269850.
Sanborn GE, Magargal LE. Venous occusive disease of the retina. In: Tasman W, Jaeger EA, eds. Duane's Ophthalmology. 2013 ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:vol 3; chap 15.
Review Date 12/19/2016
Updated by: Franklin W. Lusby, MD, ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.