Nail polish poisoning

Poisonous ingredients include:

• Toluene
• Butyl acetate
• Ethyl acetate
• Dibutyl phthalate

These ingredients can be found in various fingernail polishes.

Note: This list may not be all-inclusive.

Below are symptoms of nail polish poisoning in different parts of the body. 

BLADDER AND KIDNEYS

• Increased need to urinate

EYES, EARS, NOSE, AND THROAT

• Eye irritation and possible eye damage

GASTROINTESTINAL SYSTEM

• Nausea and vomiting
• Abdominal pain

HEART AND BLOOD CIRCULATION

• Chest pain
• Irregular heartbeat

LUNGS

• Difficulty breathing
• Slowed breathing rate
• Shortness of breath

NERVOUS SYSTEM

• Drowsiness
• Balance problems
• Coma
• Euphoria (high feeling)
• Hallucinations
• Headache
• Seizures
• Stupor (confusion, decreased level of consciousness)
• Walking problems

DO NOT make the person throw up. Seek immediate emergency medical care.

Determine the following information:

• The person's age, weight, and condition
• The name of the product (ingredients and strengths, if known)
• The time it was swallowed
• The amount swallowed

Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

Take the container with you to the hospital, if possible.

The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Blood and urine tests will be done. Symptoms will be treated as needed. The person may receive:

• Airway and breathing support, including oxygen. In extreme cases, a tube may be passed through the mouth into the lungs to prevent aspiration. A breathing machine (ventilator) would then be needed.
• Chest x-ray.
• ECG (electrocardiogram, or heart tracing).
• Endoscopy -- a camera down the throat to see burns in the esophagus and stomach.
• Fluids through a vein (by IV).
• Irrigation (washing of the skin and eyes), which may occur every few hours for several days.
• Medicines to treat symptoms.
• Skin debridement (surgical removal of burned skin).
• Tube through the mouth into the stomach (rarely) to wash out the stomach (gastric lavage).

How well a person does depends on the amount of poison swallowed and how quickly treatment is received. The faster a person gets medical help, the better the chance for recovery. Nail polish tends to come in small bottles, so serious poisoning is unlikely if only one bottle was swallowed. However, always seek immediate emergency medical care.

Some people sniff nail polish on purpose to get intoxicated (drunk) by the fumes. Over time these people, as well as those working in poorly ventilated nail salons, can develop a condition known as "painter syndrome." This is a permanent condition that causes walking problems, speech problems, and memory loss. Painter syndrome may also be called organic solvent syndrome, psycho-organic syndrome, and chronic solvent encephalopathy (CSE). CSE can also cause symptoms such as headache, fatigue, mood disturbances, sleep disorders, and possible behavioral changes.

Sudden death is possible in some nail polish poisoning cases.

Organic solvent syndrome; Psycho-organic syndrome; Chronic solvent encephalopathy

Meehan TJ. Care of the poisoned patient. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 135.

Wang GS, Buchanan JA. Hydrocarbons. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 147.

Updated by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.