Contac is the brand name for a cough, cold, and allergy medicine. It contains several ingredients, including members of the class of medicines known as sympathomimetics, which can have effects similar to adrenaline. Contac overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.
This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Poisonous Ingredient
These ingredients in Contac can be harmful in large amounts:
- Acetaminophen (Tylenol)
- Chlorpheniramine
- Dextromethorphan hydrobromide
- Diphenhydramine hydrochloride
- Pseudoephedrine hydrochloride
Note: Not all of these ingredients are found in every form of Contac.
Where Found
Besides being in Contac, these ingredients are also found in some over-the-counter herbal products advertised to help with weight loss and athletic performance.
Symptoms
Below are symptoms of a Contac overdose in different parts of the body:
BLADDER AND KIDNEYS
- Difficult or slow urination
- Inability to completely empty the bladder
EYES, EARS, NOSE, MOUTH, AND THROAT
- Blurred vision
- Enlarged (dilated) pupils
- Yellow eyes due to jaundice
HEART AND BLOOD
- Increased blood pressure
- Irregular heartbeat
- Nausea and vomiting
- Rapid heartbeat
MUSCLES AND JOINTS
- Muscle pain and spasms, tremor, unsteadiness
NERVOUS SYSTEM
- Agitation
- Convulsions (seizures)
- Depression
- Delirium (acute confusion)
- Disorientation, nervousness, hallucinations
- Drowsiness
- Fever
STOMACH AND INTESTINES
Some of these symptoms may occur, even when the medicine is taken properly.
Before Calling Emergency
Have this information ready:
- The person's age, weight, and condition
- Name of the product (ingredients and strength, if known)
- Time it was swallowed
- Amount swallowed
- If the medicine was prescribed for the person
Poison Control
The local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.
This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.
You can also get online poison help now at Poisonhelp.org. Just enter the product, poison, or medicine to get expert help.
What to Expect at the Emergency Room
Take the container with you to the hospital, if possible.
Your health care provider will measure and monitor your vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated.
Tests that may be done include:
- Blood and urine tests
- Chest x-ray
- CT scan (advanced imaging) of the brain for neurologic symptoms
- Electrocardiogram (ECG)
Treatment may include:
- Activated charcoal
- Fluids through a vein (IV)
- Medicine to treat symptoms
- Laxative
- Breathing support, including oxygen, tube through the mouth into the lungs, and breathing machine (ventilator)
Outlook (Prognosis)
This type of overdose tends to be mild. However, if the person swallowed enough of the product, serious complications (such as liver damage) can occur. This is from the acetaminophen in the product. How well a person does depends on how much was taken and how soon they receive treatment. Serious heart rhythm disturbances and death can occur.
References
Aronson JK. Ephedra, ephedrine, and pseudoephedrine. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:65-75.
Ganetsky M. Acetaminophen. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 138.
Nelson LS, Calello DP. Acute poisoning. Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 96.
Theobald JL, Corcoran JN. Poisoning. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 94.
Review Date 7/1/2025
Updated by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.