Acetone poisoning

Acetone is a chemical used in many household products. This article discusses poisoning from swallowing acetone-based products. Poisoning may also occur from breathing in fumes or absorbing it through the skin.

This is for information only and not for use in the treatment or management of an actual poison exposure. If you have an exposure, you should call your local emergency number (such as 911) or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.

Poisonous Ingredient

The poisonous ingredients include:

Acetone
Dimethyl formaldehyde
Dimethyl ketone

Where Found

Acetone can be found in:

Nail polish remover
Some cleaning solutions
Some glues, including rubber cement
Some lacquers

Other products may also contain acetone.

Symptoms

Below are symptoms of acetone poisoning or exposure in different parts of the body.

HEART AND BLOOD VESSELS (CARDIOVASCULAR SYSTEM)

Low blood pressure

STOMACH AND INTESTINES (GASTROINTESTINAL SYSTEM)

Nausea and vomiting
Pain in belly area
Person may have a fruity odor
Sweet taste in mouth

NERVOUS SYSTEM

Feeling of drunkenness
Coma (unconscious, unresponsive)
Drowsiness
Stupor (confusion, decreased level of consciousness)
Lack of coordination

BREATHING (RESPIRATORY) SYSTEM

URINARY SYSTEM

Increased need to urinate

Home Care

Seek medical help right away. Do NOT make a person throw up unless the poison control center or a health care provider tells you to.

Before Calling Emergency

Have this information ready:

The person's age, weight, and condition
The name of the product (ingredients and strength, if known)
The time it was swallowed
The amount swallowed

Poison Control

Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This hotline number will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

What to Expect at the Emergency Room

Take the container that contains the acetone with you to the hospital, if possible.

The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated. The person may receive:

Blood tests
Breathing support, including oxygen and a breathing tube through the mouth into the lungs
Chest x-ray
ECG (electrocardiogram, or heart tracing)
Intravenous fluids (IV, fluids given through a vein)
Medicines to treat symptoms
Tube through the nose into the stomach to empty the stomach (gastric lavage)

Outlook (Prognosis)

Accidentally drinking small amounts of acetone/nail polish remover is unlikely to harm you as an adult. However, even small amounts can be dangerous to your child, so it is important to keep this and all household chemicals in a safe place.

If the person survives past 48 hours, the chances for recovery are good.

Alternative Names

Dimethyl formaldehyde poisoning; Dimethyl ketone poisoning; Nail polish remover poisoning

References

Agency for Toxic Substances and Disease Registry (ATSDR) website. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service. Toxicological profile for acetone. wwwn.cdc.gov/TSP/ToxProfiles/ToxProfiles.aspx?id=5&tid=1. Reviewed July 30, 2022. Accessed April 10, 2023.

Nelson ME. Toxic alcohols. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 136.

Review Date 4/1/2023

Updated by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.