Alveolar abnormalities are changes in the tiny air sacs in the lungs, called alveoli. Alveoli allow oxygen to enter the blood. They are very thin to let oxygen move from the lungs to the blood vessels, and for carbon dioxide to be removed from the blood vessels to the lungs.
Depending on the disease, alveoli may:
- Fuse together
- Develop thickened linings
- Fill with fluid
- Fill with blood
- Fill with pus
- Get destroyed
These changes can be temporary or permanent, depending on the disease.
Albertine KH. Anatomy of the lungs. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 1.
Hall JE. Respiratory insufficiency - pathophysiology, diagnosis, oxygen therapy. In: Hall JE, ed. Guyton and Hall Textbook of Medical Physiology. 13th ed. Philadelphia, PA: Elsevier; 2016:chap 43.
Review Date 5/16/2019
Updated by: Denis Hadjiliadis, MD, MHS, Paul F. Harron, Jr. Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.