Hereditary ovalocytosis is a rare condition passed down through families (inherited). The blood cells are oval-shaped instead of round. It is a form of hereditary elliptocytosis.
Ovalocytosis is mainly found in Southeast Asian populations.
Exams and Tests
An exam by your health care provider may show an enlarged spleen.
This condition is diagnosed by looking at the shape of blood cells under a microscope. The following tests may also be done:
In severe cases, the disease may be treated by removal of the spleen (splenectomy).
The condition may be associated with gallstones or kidney problems.
Ovalocytosis - hereditary
Gallagher PG. Hemolytic anemias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 161.
Segel GB. Hereditary elliptocyctosis. In: Kliegman RM, Stanton BF, St Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016:chap 459.
Update Date 2/1/2016
Updated by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.