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Gout is caused by increased production of uric acid. Uric acid crystals accumulate in the joints, especially in the feet and legs, causing great pain and swelling.

Review Date 5/10/2019

Updated by: Linda J. Vorvick, MD, Clinical Associate Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.