In a person with Alzheimer disease, neurofibrillary tangles and plaques develop causing both structural and chemical problems in the brain. Alzheimer disease appears to disconnect areas of the brain that normally work together.
Review Date 2/4/2020
Updated by: Amit M. Shelat, DO, FACP, FAAN, Attending Neurologist and Assistant Professor of Clinical Neurology, Stony Brook University School of Medicine, Stony Brook, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.