Ehlers-Danlos syndrome (EDS) is a group of inherited disorders that weaken connective tissues. Connective tissues are proteins that support skin, bones, blood vessels, and other organs.
EDS usually affects your skin, joints and blood vessel walls. Symptoms include
- Loose joints
- Fragile, small blood vessels
- Abnormal scar formation and wound healing
- Soft, velvety, stretchy skin that bruises easily
There are several types of EDS. They can range from mild to life-threatening. About 1 in 5,000 people has EDS. There is no cure. Treatment involves managing symptoms, often with medicines and physical therapy. It also includes learning how to protect your joints and prevent injuries.
- Ehlers-Danlos Syndrome (Mayo Foundation for Medical Education and Research)
- Ehlers-Danlos syndrome (Medical Encyclopedia) Also in Spanish
- Ehlers-Danlos Syndrome Hypermobility Type (Marfan Foundation) - PDF
- Ehlers-Danlos Syndrome: Causes and Symptoms (Ehlers-Danlos Syndrome Network C.A.R.E.S.)
- Ehlers-Danlos Syndrome: Myths and Facts (Ehlers-Danlos Syndrome Network C.A.R.E.S.)
- Heritable Disorders of Connective Tissue (National Institute of Arthritis and Musculoskeletal and Skin Diseases)
- Genetics Home Reference: Ehlers-Danlos syndrome (National Library of Medicine)
- ClinicalTrials.gov: Ehlers-Danlos Syndrome (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Orthostatic Intolerance and Postural Orthostatic Tachycardia Syndrome in Joint Hypermobility...
- Article: Defect in dermatan sulfate in urine of patients with Ehlers-Danlos...
- Article: P3h3-null and Sc65-null Mice Phenocopy the Collagen Lysine Under-hydroxylation and...
- Ehlers-Danlos Syndrome -- see more articles