Ehlers-Danlos syndrome (EDS) is a group of inherited disorders that weaken connective tissues. Connective tissues are proteins that support skin, bones, blood vessels, and other organs.
EDS usually affects your skin, joints and blood vessel walls. Symptoms include
- Loose joints
- Fragile, small blood vessels
- Abnormal scar formation and wound healing
- Soft, velvety, stretchy skin that bruises easily
There are several types of EDS. They can range from mild to life-threatening. About 1 in 5,000 people has EDS. There is no cure. Treatment involves managing symptoms, often with medicines and physical therapy. It also includes learning how to protect your joints and prevent injuries.
- Ehlers-Danlos syndrome (Medical Encyclopedia) Also in Spanish
- Ehlers-Danlos Syndrome (Mayo Foundation for Medical Education and Research)
- Ehlers-Danlos Syndrome Hypermobility Type (Marfan Foundation) - PDF
- Heritable Disorders of Connective Tissue (National Institute of Arthritis and Musculoskeletal and Skin Diseases)
- Genetics Home Reference: Ehlers-Danlos syndrome (National Library of Medicine)
- ClinicalTrials.gov: Ehlers-Danlos Syndrome (National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Vascular Ehlers-Danlos syndrome with cryptorchidism, recurrent pneumothorax, and pulmonary capillary...
- Article: Transcriptome analysis of skin fibroblasts with dominant negative COL3A1 mutations...
- Article: Dermal fibroblast-to-myofibroblast transition sustained by αvß3 integrin-ILK-Snail1/Slug signaling is a...
- Ehlers-Danlos Syndrome -- see more articles
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