Small bowel biopsy is a diagnostic procedure in which a portion of the small bowel lining is removed for examination. A flexible fiberoptic or video tube (endoscope) is inserted through your mouth or nose and into the upper gastrointestinal tract where a tissue sample is removed. This test is most often performed to help diagnose diseases of the small intestines.
Review Date 10/17/2019
Updated by: Michael M. Phillips, MD, Clinical Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.