A coloboma is a defect in the iris of the eye. It can appear as a black notch of varying depth at the edge of the pupil, giving the pupil an irregular shape. Coloboma may be associated with hereditary conditions, trauma to the eye, or eye surgery.
Review Date 12/2/2017
Updated by: Franklin W. Lusby, MD, ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.