Overview
Tissue necrosis caused by distal capillary thrombosis resulting from cryoglobulin precipitation in the vessels. The black tissue under the nails is ischemic, and will eventually slough, or be reabsorbed by the body.
Review Date 1/31/2021
Updated by: Diane M. Horowitz, MD, Rheumatology and Internal Medicine, Northwell Health, Great Neck, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.