Granulomatosis with polyangiitis is a disease that can affect many organ systems (systemic) and primarily causes lung (pulmonary) and kidney (renal) disease, but is also capable of affecting the skin.
Review Date 10/18/2019
Updated by: Gordon A. Starkebaum, MD, MACR, ABIM Board Certified in Rheumatology, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.