Granulomatosis with polyangiitis is a disease that can affect many organ systems (systemic) and primarily causes lung (pulmonary) and kidney (renal) disease, but is also capable of affecting the skin.
Review Date 10/1/2017
Updated by: Gordon A. Starkebaum, MD, Professor of Medicine, Division of Rheumatology, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 09/07/2018.