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Tuberous sclerosis - hypopigmented macule

Tuberous sclerosis - hypopigmented macule

Overview

This area of decreased pigment (hypopigmentation) is referred to as an "ash leaf macule" and is seen with the inherited disorder, tuberous sclerosis. Another finding, "confetti hypopigmentation" is evident as scattered white spots around the ash leaf spot.

Review Date 8/14/2026

Updated by: Christopher Simotas, MD, Assistant Professor of Pediatrics, Division of Medical Genetics, Rutgers Robert Wood Johnson School of Medicine, New Brunswick, NJ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.