The typical skin lesion of hand, foot, and mouth disease includes small blisters (vesicles) with bright red (erythematous) borders. These are typically on the pads of the fingers and palms of the hands, but can also be found on the sole of the foot, as in this picture.
Review Date 7/19/2021
Updated by: Linda J. Vorvick, MD, Clinical Associate Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.