Endocardial cushion defect is an abnormal heart condition which occurs during the development of the baby. In this condition there is no separation between the chambers of the heart. Without the separation, oxygen-rich and oxygen-poor blood mix causing the heart to work harder. Endocardial cushion defect is strongly associated with several genetic abnormalities.
Review Date 5/16/2018
Updated by: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.