Gangrene is the death of tissue in part of the body. Gangrene can occur when a body part loses its blood supply. This may happen from, for example, injury or infection.
Review Date 9/1/2021
Updated by: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.