Biguanides (Metformin) tell the liver to decrease its production of glucose, which lowers glucose levels in the bloodstream.
Review Date 1/26/2020
Updated by: Brent Wisse, MD, board certified in Metabolism/Endocrinology, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.