Histoplasmosis is a fungal infection caused by inhaling dust from spore-infected bird droppings. In the disseminated form, infection spreads throughout the body from the lungs. The death rate is fairly high for people with untreated widespread (disseminated) histoplasmosis, but is reduced significantly with treatment.
Review Date 12/4/2022
Updated by: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.