The bone disease osteoporosis is caused by more bone matrix being resorbed than being deposited. This imbalance results in a progressive loss of bone density and a thinning of bone tissue. Osteoporotic bones are more porous and therefore more vulnerable to fracture.
Review Date 4/29/2022
Updated by: Sandeep K. Dhaliwal, MD, board-certified in Diabetes, Endocrinology, and Metabolism, Springfield, VA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.