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Primary and secondary hypothyroidism

Primary and secondary hypothyroidism

Overview

Hypothyroidism is a decreased activity of the thyroid gland which may affect all body functions. The rate of metabolism slows causing mental and physical sluggishness. The most severe form of hypothyroidism is myxedema, a medical emergency. Hypothyroidism can be caused by a problem with the thyroid itself (primary), or by the malfunction of the pituitary gland or hypothalamus (secondary).

Update Date 4/23/2015

Updated by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.