An official website of the United States government
Here’s how you know
Official websites use .gov A
.gov website belongs to an official government
organization in the United States.
Secure .gov websites use HTTPS A
lock (
) or https:// means you’ve safely connected to
the .gov website. Share sensitive information only on official,
secure websites.
URL of this page: //medlineplus.gov/ency/imagepages/1518.htm
Cryoglobulinemia of the fingers
Overview
Cryoglobulinemia is caused by an abnormal protein that is occasionally found in the blood of people with multiple myeloma, leukemia, and certain forms of pneumonia. It causes blood to gel at low temperatures. In this picture, cryoglobulinemia has reduced blood flow in the fingers so much the fingers have turned dark. The black areas are gangrene resulting from lack of blood flow.
Review Date 4/1/2025
Updated by: Linda J. Vorvick, MD, Clinical Professor Emeritus, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
