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Hypersegmented PMN (Close-up)

Hypersegmented PMN (Close-up)

Overview

This image shows a large polymorphonuclear leukocyte (PMN) with multiple discretely-identifiable nuclear lobes. It can be seen in megaloblastic anemias. Normal PMN's have less than or equal to 5 lobes.

Review Date 1/19/2018

Updated by: Richard LoCicero, MD, private practice specializing in Hematology and Medical Oncology, Longstreet Cancer Center, Gainesville, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.