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Hypersegmented PMN (Close-up)

Hypersegmented PMN (Close-up)


This image shows a large polymorphonuclear leukocyte (PMN) with multiple discretely-identifiable nuclear lobes. It can be seen in megaloblastic anemias. Normal PMN's have less than or equal to 5 lobes.

Review Date 2/1/2016

Updated by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.