This image shows a large polymorphonuclear leukocyte (PMN) with multiple discretely-identifiable nuclear lobes. It can be seen in megaloblastic anemias. Normal PMN's have less than or equal to 5 lobes.
Review Date 1/25/2022
Updated by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.