Childhood disintegrative disorder is a condition in which children develop normally through about age 3. Then, over a few months, they lose language, motor, social, and other skills that they already learned.
Childhood disintegrative disorder is a part of the larger developmental disorder category of autism spectrum disorder.
Bridgemohan CF. Autism spectrum disorder. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 54.
Centers for Disease Control and Prevention website. Autism spectrum disorder, family health history and genetics. www.cdc.gov/genomics/disease/autism.htm. Updated May 18, 2022. Accessed June 26, 2023.
Centers for Disease Control and Prevention website. What is autism spectrum disorder? www.cdc.gov/ncbddd/autism/facts.html. Updated December 9, 2022. Accessed June 26, 2023.
Chaves-Gnecco D, Feldman HM. Developmental/behavioral pediatrics. In: Zitelli BJ, McIntire SC, Nowalk AJ, Garrison J, eds. Zitelli and Davis' Atlas of Pediatric Physical Diagnosis. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 3.
Sidhu R, O'Banion D, Hall C. Autism and other neurodevelopmental disabilities. Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 90.
Review Date 4/28/2023
Updated by: Neil K. Kaneshiro, MD, MHA, Clinical Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.